Browse our latest Developmental Biology articles

Page 10 of 221
    1. Developmental Biology

    Dorsoventral-mediated Shh induction is required for axolotl limb regeneration

    Sakiya Yamamoto, Saya Furukawa ... Akira Satoh
    Dorsoventral contact in axolotl limb blastemas induces Shh, showing how positional identities cooperate to drive the regeneration process.
    1. Developmental Biology
    2. Genetics and Genomics

    Single-cell transcriptomics of X-ray irradiated Drosophila wing discs reveals heterogeneity related to cell-cycle status and cell location

    Joyner Cruz, William Y Sun ... Iswar K Hariharan
    Even in a simple epithelial tissue that is exposed uniformly to X-ray irradiation, cells show marked differences in their transcriptional response based on their location and cell-cycle status.
    1. Developmental Biology

    Jam2 Signaling Functions Downstream of Hand2 To Initiate The Formation Of Organ-Specific Vascular Progenitors In Zebrafish

    Martyna Griciunaite, Julius Martinkus ... Saulius Sumanas
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Developmental Biology

    The Drosophila EGF domain protein uninflatable sets the switch between wrapping glia growth and axon wrapping instructed by Notch

    Marie Baldenius, Steffen Kautzmann ... Christian Klämbt
    In Drosophila larva, the Uninflatable protein helps to switch from FGF-receptor triggered glial growth to Notch triggered wrapping of peripheral axons.
    1. Developmental Biology

    Single-nucleus transcriptional and chromatin accessibility analyses of maturing mouse Achilles tendon uncover the molecular landscape of tendon stem/progenitor cells

    Hiroki Tsutsumi, Tomoki Chiba ... Hiroshi Asahara
    Single-cell profiling reveals CD55+CD248+ tendon stem/progenitor cells.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Branched actin polymerization drives invasive protrusion formation to promote myoblast fusion during mouse skeletal muscle regeneration

    Yue Lu, Tezin Walji ... Elizabeth H Chen
    Branched actin cytoskeleton is critical for myoblast fusion during mouse skeletal muscle regeneration.
    Version of Record
    Short Report
    • Valuable
    • Convincing
    1. Developmental Biology

    Limb Patterning: The cellular logic of limb regeneration

    Matthew Cherubino, Catherine D McCusker
    Hierarchical communication between cells with distinct positional memories orchestrates the regeneration of missing limb structures in axolotls.
    Version of Record
    Insight
    1. Developmental Biology

    Patient-specific iPSC models of neural tube defects identify underlying deficiencies in neuroepithelial cell shape regulation and differentiation

    Ioakeim Ampartzidis, Elliott M Thompson ... Gabriel L Galea
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Developmental Biology

    Human spinal cord organoids reveal cell intercalation as a conserved mechanism for secondary neurulation

    José Blanco-Ameijeiras, Yara El Majzoub ... Elisa Martí
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Computational and Systems Biology
    2. Developmental Biology

    Anti-resonance in developmental signaling regulates cell fate decisions

    Samuel J Rosen, Olivier Witteveen ... Maxwell Z Wilson
    Human cells decode dynamics Wnt signals using an anti-resonant filter that suppresses intermediate-frequency inputs and is capable of redirecting developmental fate outcomes, including germ-layer specification.