Browse our latest Developmental Biology articles

Page 10 of 215
    1. Developmental Biology

    Pu.1/Spi1 dosage controls the turnover and maintenance of microglia in zebrafish and mammals

    Yi Wu, Weilin Guo ... Tao Yu
    Pu.1-P53 axis controls the turnover and maintenance of microglia by cell competition.
    1. Developmental Biology

    SoxB1 family members inhibit Wnt signaling to promote maturation and deposition of stable neuromasts by the zebrafish Posterior Lateral Line primordium

    Greg Palardy, Kyeong-won Yoo ... Ajay B Chitnis
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Cell Biology
    2. Developmental Biology

    Inducible, virus-free direct lineage reprogramming enhances scalable generation of human inner ear hair cell-like cells

    Robert N Rainey, Sam D Houman ... Neil Segil
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Cell Biology
    2. Developmental Biology

    Female-germline specific protein Sakura interacts with Otu and is crucial for germline stem cell renewal and differentiation and oogenesis

    Azali Azlan, Li Zhu, Ryuya Fukunaga
    Sakura is expressed in female germlines, interacts with Otu, and is crucial for germline stem cell renewal and differentiation and oogenesis in Drosophila.
    1. Cell Biology
    2. Developmental Biology

    Human formin FHOD3-mediated actin elongation is required for sarcomere integrity in cardiomyocytes

    Dylan A Valencia, Angela N Koeberlein ... Margot E Quinlan
    Complementary biochemical and cell-biological approaches reveal that formin FHOD3-mediated actin elongation, rather than nucleation, is critical for maintaining cardiomyocyte sarcomeres.
    1. Developmental Biology
    2. Computational and Systems Biology

    A quantitative pipeline for whole-mount deep imaging and analysis of multi-layered organoids across scales

    Alice Gros, Jules Vanaret ... Sham Tlili
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    PRDM16 functions as a co-repressor in the BMP pathway to suppress neural stem cell proliferation

    Li He, Jiayu Wen, Qi Dai
    PRDM16 directs BMP signaling outcomes by guiding SMAD complex genomic binding to repress neural stem cell proliferation and promote choroid plexus epithelial specification.
    1. Developmental Biology

    NR2F2 is required in the embryonic testis for fetal Leydig cell development

    Aitana Perea-Gomez, Natividad Bellido Carreras ... Marie-Christine Chaboissier
    NR2F2 regulates fetal Leydig cell differentiation and steroidogenesis in mouse testes, providing mechanistic insight into testis development and the etiology of 46,XY differences in sex development.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Cardiac Repair: Aiming for spatial and temporal control of gene expression

    Stanislao Igor Travisano, Ching-Ling Lien
    Bioluminescent imaging is helping researchers better understand the effectiveness of tissue regeneration enhancers delivered to injured heart tissue by different adeno-associated virus vectors.
    Version of Record
    Insight
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    Drosophila hamlet mediates epithelial tissue assembly of the reproductive system

    Huazhen Wang, Ludivine Bertonnier-Brouty ... Qi Dai
    Hamlet regulates heterotypic epithelial fusion by controlling spatial and temporal expression of known and novel epithelial regulators like Wnt and Tl pathway components, a mechanism potentially conserved through evolution.
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