Browse our latest Developmental Biology articles

Page 11 of 217
    1. Developmental Biology

    Redistribution of fragmented mitochondria ensures symmetric organelle partitioning and faithful chromosome segregation in mitotic mouse zygotes

    Haruna Gekko, Ruri Nomura ... Takuya Wakai
    Depletion of Dynamin-related protein 1, a key regulator of mitochondrial fission, in mouse zygotes impair symmetric organelle partitioning and chromosome segregation leading to early developmental arrest.
    1. Developmental Biology

    Long-term live imaging, cell identification and cell tracking in regenerating crustacean legs

    Çağrı Çevrim, Béryl Laplace-Builhé ... Michalis Averof
    Live imaging allows tracking cellular behaviours and cell fates during the entire course of leg regeneration, spanning approximately one week, in a crustacean model.
    1. Developmental Biology

    Molecular and mechanical signatures contributing to mouse epidermal differentiation and barrier formation

    Alexandra Prado-Mantilla, Wenxiu Ning, Terry Lechler
    The roles of intermediate cells and contractility are characterized in the embryonic development of the epidermis.
    1. Developmental Biology

    Identification and characterization of early human photoreceptor states and cell-state-specific retinoblastoma-related features

    Dominic WH Shayler, Kevin Stachelek ... David Cobrinik
    Full-length single-cell RNA-sequencing provide insights into the earliest gene expression programs, the distinct mRNA transcript isoforms, and the retinoblastoma-related cell states associated with human cone and rod photoreceptor development.
    1. Developmental Biology

    Cytoneme-mediated intercellular signaling in keratinocytes is essential for epidermal remodeling in zebrafish

    Yi Wang, Thomas Nguyen ... Dae Seok Eom
    Keratinocyte cytonemes mediate essential Notch signaling for proper skin maintenance, with their disruption leading to abnormal differentiation and hyperproliferation resembling human skin disease phenotypes.
    1. Developmental Biology

    Meteorins regulate the formation of the left-right organizer and the establishment of vertebrate body asymmetry

    Fanny Eggeler, Jonathan Boulanger-Weill ... Filippo Del Bene
    Genetic analyses in zebrafish reveal a new role for the Meteorin protein family in the left-right asymmetry patterning during embryonic vertebrate development.
    1. Developmental Biology

    Single-cell transcriptomes of zebrafish germline reveal progenitor types and feminization by Foxl2l

    Chen-wei Hsu, Hao Ho ... Bon-chu Chung
    A single-cell transcriptomic study characterizes foxl2l-expressing germ cell progenitors important for female development in zebrafish and reveals the mechanism of sex differentiation.
    1. Developmental Biology
    2. Genetics and Genomics

    Coordinated Tbx3/Tbx5 transcriptional control of the adult ventricular conduction system

    Ozanna Burnicka-Turek, Katy A Trampel ... Ivan P Moskowitz
    Coordinated removal of Tbx3 and Tbx5 function alters the molecular features of the fast ventricular cardiac conduction system toward non-conduction working myocardium, illuminating transcriptional control of cardiac conduction system patterning.
    1. Developmental Biology

    Contraction-induced endocardial id2b plays a dual role in regulating myocardial contractility and valve formation

    Shuo Chen, Jinxiu Liang ... Peidong Han
    Endocardial id2b integrates biomechanical cues to orchestrate valve formation and myocardial maturation during cardiac development.