Quantitative Drosophila pupal wing experiments support planar polarity depending on cell-scale signalling that does not involve depletion of a limited pool of core proteins or polarised transport on microtubules.
A collaborative open-source platform enabling interactive 3D visualization, quantitative evaluation, and expert curation of complex biological morphologies to enhance the quality and reproducibility of large-scale imaging studies.
Eed, a core subunit of Polycomb repressive complex 2, is required for craniofacial osteoblast differentiation and mesenchymal proliferation after induction of the neural crest.
Rebecca Garrett Jaszczak, Jay W Zussman ... Diana J Laird
A temporal and positional atlas of mouse primordial germ cell (PGC) migration reveals dynamic gene expression and somatic cell interactions that suggest how changing migratory niches regulate PGC development.
Caleb CS Calhoun, Mary ES Capps ... Summer B Thyme
Sensitive brain activity mapping and behavioral profiling reveal most microexons are dispensable for early brain development but highlight a small subset with intriguing neural phenotypes for future study.
