Keratinocyte cytonemes mediate essential Notch signaling for proper skin maintenance, with their disruption leading to abnormal differentiation and hyperproliferation resembling human skin disease phenotypes.
Fanny Eggeler, Jonathan Boulanger-Weill ... Filippo Del Bene
Genetic analyses in zebrafish reveal a new role for the Meteorin protein family in the left-right asymmetry patterning during embryonic vertebrate development.
A single-cell transcriptomic study characterizes foxl2l-expressing germ cell progenitors important for female development in zebrafish and reveals the mechanism of sex differentiation.
Ozanna Burnicka-Turek, Katy A Trampel ... Ivan P Moskowitz
Coordinated removal of Tbx3 and Tbx5 function alters the molecular features of the fast ventricular cardiac conduction system toward non-conduction working myocardium, illuminating transcriptional control of cardiac conduction system patterning.
Analyses of zebrafish meioc mutants revealed that spermatogonial stem cells with low rRNA transcription caused by nucleolar Piwil1 require Meioc to keep Piwil1 in cytoplasm for the upregulation of rRNA transcription necessary for differentiation.
