Browse our latest Developmental Biology articles

Page 11 of 223
    1. Developmental Biology
    2. Genetics and Genomics

    Drosophila melanogaster model of RVCL-S demonstrates age dependent disease progression

    Elena Gracheva, Abigail Matt ... Chao Zhou
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Developmental Biology

    Progressive mural cell deficiencies across the lifespan in a foxf2 model of cerebral small vessel disease

    Merry Faye E Graff, Emma EM Heeg ... Sarah J Childs
    Loss of foxf2 in zebrafish leads to a reduced pericyte progenitor pool in embryos and progresses to severe cerebrovascular defects over the lifespan, suggesting that cerebral small vessel disease in adults has roots in development.
    1. Developmental Biology
    2. Neuroscience

    Developmental sleep reallocation enables metabolic adaptation in desert flies

    Shuhao Li, Milan Szuperak ... Matthew S Kayser
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Developmental Biology

    Genetic network shaping Kenyon cell identity and function in Drosophila mushroom bodies

    Pei-Chi Chung, Kai-Yuan Ku ... Hung-Hsiang Yu
    The genetic network of BTB zinc finger transcription factors and Eip93F is crucial for Kenyon cell identity regulation and neuronal function acquisition in the construction of Drosophila mushroom bodies.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    Massively parallel reporter assay for mapping gene-specific regulatory regions at single-nucleotide resolution

    Alastair J Tulloch, Ryan Nicholas Delgado ... Constance L Cepko
    Integrated locus-specific and mutational MPRAs reveal regulatory modules and nucleotide determinants governing cell type-specific gene expression, providing a scalable framework for mapping cis-regulatory architecture.
    1. Developmental Biology

    Cytoplasmatic polyadenylation of mRNA by TENT5A is critical for enamel mineralization

    Goretti Aranaz-Novaliches, Olga Gewartowska ... Jan Prochazka
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Developmental Biology
    2. Neuroscience

    Cell cycle-dependent cues regulate temporal patterning of the Drosophila central brain neural stem cells

    Gonzalo N Morales Chaya, Mubarak Hussain Syed
    Intrinsic cell cycle progression governs developmental time in neural stem cells by regulating temporal gene transitions that generate neural diversity.
    1. Developmental Biology

    Oocyte Development: The discovery of the mammalian fusome

    Michael Buszczak, Anirban Dasgupta
    The presence of an organelle called the fusome in species as diverse as Drosophila and mammals indicates an ancient, conserved programme of germ cell development.
    Version of Record
    Insight
    1. Developmental Biology

    Trehalose metabolism regulates transcriptional control of muscle development in lepidopteran insects

    Sharada Mohite, Tanaji Devkate ... Rakesh Shamsunder Joshi
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Cell Biology
    2. Developmental Biology

    BICC1 interacts with PKD1 and PKD2 to drive cystogenesis in ADPKD

    Uyen Tran, Andrew J Streets ... Oliver Wessely
    The RNA-binding protein BICC1 can act as a genetic disease modifier for kidney cyst formation, potentially explaining the high variability of disease onset and severity in autosomal-dominant polycystic kidney disease patients.