The hemogenic gastruloid model of embryonic blood development captures multi-wave haematopoiesis and enables interrogation of infant leukaemia cell-of-origin.
Functional organoids prepared from chicken embryonic gut consisting of pacemaker cells and smooth muscles undergo periodic contractions, offering a useful tool to understand rhythm control in multicellular systems.
Disrupting full-length BEND2 impairs ovarian reserve establishment without causing male sterility, highlighting a sex-specific role in fertility and offering new insights into genetic contributions to infertility diagnosis and reproductive health.