Browse our latest Developmental Biology articles

Studies with mice and brain organoids models reveals that dysregulation of GTF2IRD1-TTR-ERK pathway significantly contributes to neuronal deficits of Williams syndrome.

Histone deacetylase 2 (HDAC2) and polycomb repressive complex 2 (PRC2) control endothelial gene expression for BBB development and prevented Wnt/β-catenin target genes from being expressed in adult CNS ECs.

CCDC113 is a key structural hub for sperm axoneme and head-tail coupling apparatus (HTCA) stability, with defects leading to male infertility through disruption of sperm flagellar and HTCA integrity.

The speed of intraflagellar transport, influenced by particle size, shows a positive correlation with ciliary length in zebrafish.

Marcks and Marcks-like 1 proteins are required for normal neurite formation and proliferation of neuro-glial progenitors during development and regeneration of the Xenopus spinal cord implicating these proteins as critical new factors for spinal cord development and regeneration.

Reduced lung myofibroblast proliferation is a unifying feature in multiple models of developmental emphysema and inhibition of myofibroblast proliferation is sufficient to cause this pathology.

Cells called alveolar myofibroblasts, which have a central role in the development of the lung after birth, receive an orchestrated input from a range of different signaling pathways.

A transcriptomic atlas of the mouse vomeronasal organ reveals novel receptor co-expression patterns and provides a framework for understanding sensory neuron lineage and receptor specification.

Aneuploid human embryonic cells are eliminated by p53-mediated apoptosis in a gene dosage dependent manner.

Drosophila melanogastereven-skipped enhancers control transcriptional bursting by modulating frequency and amplitude, regardless of varying transcription factor inputs, even when mutated to express in embryonic regions not under selective pressure.