Browse our latest Developmental Biology articles

Triglyceride plays an important role in regulating sperm development.

In cardiac ischemia/reperfusion injury, resident macrophages orchestrate the immune response and positively influence postinfarct remodeling, whereas recruited macrophages determine infarct size.

Single-cell expression profiling and genetic lineage analysis show that aging impairs adipocyte differentiation from precursor cells and blocks the thermogenic activation of adipocytes during cold exposure.

FMNL2 associates with Formin2 and Arp2/3 complex for actin assembly, which further regulates spindle migration and INF2/Cofilin-related organelle dynamics during mammalian oocyte maturation.

Live imaging of the Notch co-activator Mastermind reveals that it promotes the formation of a dynamic transcription hub in Notch ON nuclei, conferring probabilistic transcription and providing a template for signal memory.

At the onset of gastrulation, primitive streak morphogenesis that requires mitosis along the embryo midline, persists even with a disrupted bilateral cell flow.

Geometric criteria can be used to assess whether cell intercalation is active or passive during the convergent extension of tissue.

A mouse model of maturity-onset diabetes of the young illuminates that overactive TALK-1 channels limit β-cell calcium influx through membrane potential hyperpolarization, which blunts insulin secretion and causes glucose intolerance.

AlphaFold-Multimer was used to investigate extracellular protein interactions involved in mammalian egg-sperm recognition, suggesting a putative pentameric complex that includes TMEM81, a sperm protein not previously involved in gamete recognition.