Oguzhan F Baltaci, Andrea Usseglio Gaudi ... Benjamin M Hogan
Pericytes regulate cerebrovascular development, while vascular smooth muscle cells prevent hemorrhage and blood–brain barrier breakdown at vascular hotspots in juvenile and adult zebrafish.
Gustavo Aguilar, Michèle E Sickmann ... Martin Müller
Early enhancer logic precisely aligns developmental boundaries by integrating HOX, GATA, and signaling inputs, ensuring correct tissue patterning and preventing mirror-image duplications in the developing wing.
The Tapenade pipeline enables single-cell, whole-mount 3D quantification in dense multilayer organoids, linking spatial gene co-expression and nuclear deformation to emerging tissue-scale organization.
Exploring the differentiation of iPSC to trunk tenocytes and how the single-cell RNA sequencing and pathway analysis can assist in making it more specific.
William Salvidge, Chris Brimson ... Chris Thompson
Experiments and mathematical modelling show cell fate in Dictyostelium discoideum partly depends on cell-cycle phase, but also on stochastic gene-expression variability which enhances robustness of developmental responses to cell-cycle perturbation.
