Browse our latest Developmental Biology articles

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    1. Developmental Biology

    Patient-specific iPSC models of neural tube defects identify underlying deficiencies in neuroepithelial cell shape regulation and differentiation

    Ioakeim Ampartzidis, Elliott M Thompson ... Gabriel L Galea
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Computational and Systems Biology
    2. Developmental Biology

    Anti-resonance in developmental signaling regulates cell fate decisions

    Samuel J Rosen, Olivier Witteveen ... Maxwell Z Wilson
    Human cells decode dynamics Wnt signals using an anti-resonant filter that suppresses intermediate-frequency inputs and is capable of redirecting developmental fate outcomes, including germ-layer specification.
    1. Cell Biology
    2. Developmental Biology

    Bruce suppresses autophagy-regulated caspase activity and wing tissue growth in Drosophila

    Natsuki Shinoda, Yutaro Hama ... Masayuki Miura
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Developmental Biology

    Permissive and instructive Hox codes govern limb positioning

    Yajun Wang, Maik Hintze ... Ruijin Huang
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Incomplete
    1. Developmental Biology

    Progressive mural cell deficiencies across the lifespan in a foxf2 model of Cerebral Small Vessel Disease

    Merry Faye E Graff, Emma EM Heeg ... Sarah J Childs
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Developmental Biology

    Glial betaPix is essential for blood vessel development in the zebrafish brain

    Shihching Chiu, Qinchao Zhou ... Jing-Wei Xiong
    The glial-specific role of betaPix during cerebral blood vessel development has been revealed by establishing a new betaPix conditional trap allele in zebrafish.
    1. Developmental Biology

    Rtf1-dependent transcriptional pausing regulates cardiogenesis

    Adam D Langenbacher, Fei Lu ... Jau-Nian Chen
    Genetic approaches identify Rtf1-dependent transcriptional pausing as an essential mechanism governing the deployment of the cardiac gene program during myocardial differentiation from the mesoderm.
    1. Developmental Biology
    2. Neuroscience

    Afadin sorts different retinal neuron types into accurate cellular layers

    Matthew R Lum, Sachin Patel ... Xin Duan
    Genetic perturbation of Afadin in the retina reveals its importance for the precise organization of the retinal layers while leaving neuronal fate and numbers unaffected.
    Version of Record
    Short Report
    • Important
    • Solid
    1. Developmental Biology
    2. Computational and Systems Biology

    A quantitative pipeline for whole-mount deep imaging and analysis of multi-layered organoids across scales

    Alice Gros, Jules Vanaret ... Sham Tlili
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Developmental Biology
    2. Neuroscience

    Comparative developmental transcriptomics of Drosophila mushroom body neurons highlights the mevalonate pathway as a regulator of axon growth

    Lora Fahdan, Hagar Meltzer ... Oren Schuldiner
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete