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    1. Cell Biology
    2. Developmental Biology

    Prickle and Ror modulate Dishevelled-Vangl interaction to regulate non-canonical Wnt signaling during convergent extension in Xenopus

    Hwa-seon Seo, Deli Yu ... Jianbo Wang
    During convergent extension morphogenesis, non-canonical Wnt induces the signal transducer Dishevelled to transition from Vangl to Frizzled, a process that is inhibited by Prickle but facilitated by the co-receptor Ror.
    1. Developmental Biology

    Arrayed single-gene perturbations identify drivers of human anterior neural tube closure

    Roya E Huang, Giridhar M Anand ... Sharad Ramanathan
    Revised
    Reviewed Preprint v2
    Updated
    • Landmark
    • Exceptional
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    The long-range gene regulatory landscape of cerebellar granule neuron progenitors

    Kimberley LH Riegman, Charlotte George ... M Albert Basson
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Developmental Biology
    2. Neuroscience

    Neurotrophin-3 produced by motor neurons non-cell autonomously regulate the development of pre-motor interneurons in the developing spinal cord

    Andrea Angla-Navarro, Ana Dominguez Bajo ... Frédéric Clotman
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Developmental Biology

    A quantitative in vivo CRISPR-imaging platform identifies regulators of hyperplastic and hypertrophic adipose morphology in zebrafish

    Rebecca Wafer, Panna Tandon, James Minchin
    A scalable zebrafish imaging platform reveals that Foxp1 paralogues have non-redundant roles in developmental patterning of adipose morphology and adaptive remodelling capacity in response to a high-fat diet.
    1. Developmental Biology
    2. Immunology and Inflammation

    HEB collaborates with TCR signaling to upregulate Id3 and enable γδT17 cell maturation in the fetal thymus

    Johanna S Selvaratnam, Juliana DB da Rocha ... Michele Kay Anderson
    Dynamic regulation of the E-protein/Id axis links TCR signaling to the maturation of IL-17-producing γδ T cells.
    1. Developmental Biology

    A cell atlas of the developing human outflow tract of the heart and its adult aortic valve derivatives

    Rotem Leshem, Syed Murtuza Baker ... Nicoletta Bobola
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology
    2. Developmental Biology

    Zinc is a Key Regulator of the Sperm-Specific K+ Channel (Slo3) Function

    Rizki Tsari Andriani, Tanadet Pipatpolkai ... Takafumi Kawai
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Developmental Biology
    2. Genetics and Genomics

    Single-cell co-mapping reveals relationship between chromatin state and gene expression in early zebrafish development

    Vivek Bhardwaj, Alberto Griffa ... Alexander van Oudenaarden
    A robust and quantitative map links chromatin modification and gene expression of cells during zebrafish embryogenesis.
    1. Developmental Biology
    2. Evolutionary Biology

    The endoderm cell trajectory of urochordate Styela clava reveals the dual developmental origin and evolution of digestive tract

    Yonghang Ge, Wei Zhang ... Jiankai Wei
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
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