The blueprint and narrative of shape formation during early development can be objectively observed by quantifying and analyzing whole-embryo dynamics.
BCAS2 directly binds to the Armadillo repeats 9–12 of β-catenin via the coiled-coil domains, sequestering β-catenin within the nucleus and thereby promoting Wnt signaling during primitive hematopoiesis.
A temporally stable and cell-type-specific genetic driver library provides the means to access and manipulate neuronal lineages in the fly nervous system during development and adulthood.