Browse our latest Developmental Biology articles

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    1. Developmental Biology

    Sox9 prevents retinal degeneration and is required for limbal stem cell differentiation in the adult mouse eye

    Alicia Hurtado, Víctor López-Soriano ... Francisco J Barrionuevo
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Convincing
    1. Developmental Biology
    2. Neuroscience

    Segment-specific axon guidance by Wnt/Fz signaling diversifies motor commands in Drosophila larvae

    Suguru Takagi, Shiina Takano ... Akinao Nose
    Rewiring the command neurons in the tactile circuit is sufficient to change the behavioral strategy of a whole animal, implying a 'plug-and-play' flexibility in sensorimotor circuits.
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    Nucleation-dependent propagation of Polycomb modifications emerges during the Drosophila maternal to zygotic transition

    Natalie Gonzaga-Saavedra, Eleanor A Degen ... Shelby A Blythe
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Developmental Biology

    Atoh1 is required for the formation of lateral line electroreceptors and hair cells, whereas FoxG1 represses an electrosensory fate

    Martin Minařík, Alexander S Campbell ... Clare VH Baker
    Targeting Atoh1 for CRISPR/Cas9-mediated mutagenesis in sturgeon results in missing electroreceptors as well as mechanosensory hair cells, supporting conserved developmental mechanisms, whereas ectopic electrosensory organs develop after targeting mechanosensory-restricted Foxg1, suggesting FoxG1 directly or indirectly represses electrosensory organ formation.
    1. Cell Biology
    2. Developmental Biology

    Sulfation affects apical extracellular matrix organization during development of the Drosophila embryonic salivary gland tube

    J Luke Woodward, Jeffrey Matthew ... SeYeon Chung
    Sulfation is required for organizing the apical extracellular matrix during tubular organ formation.
    1. Developmental Biology
    2. Neuroscience

    Ptbp1 is not required for retinal neurogenesis and cell fate specification

    Haley Appel, Rogger P Carmen-Orozco ... Seth Blackshaw
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Developmental Biology

    Morphogenesis: Regulating closure of the neural tube in humans

    Leon Qarawani, Jacob H Hanna
    An organoid-based screening platform that allows one-gene-at-a-time knockdown across a whole tissue has been used to identify the genes that regulate closure of the neural tube in humans.
    Version of Record
    Insight
    1. Developmental Biology
    2. Neuroscience

    Removal of developmentally regulated microexons has a minimal impact on larval zebrafish brain morphology and function

    Caleb CS Calhoun, Mary ES Capps ... Summer B Thyme
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Cell Biology
    2. Developmental Biology

    The oocyte zinc transporter Slc39a10/Zip10 is a regulator of zinc sparks during fertilization in mice

    Atsuko Kageyama, Narumi Ogonuki ... Junya Ito
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Developmental Biology

    Extracellular adenosine deamination primes tip organizer development in Dictyostelium

    Pavani Hathi, Baskar Ramamurthy
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing