Browse our latest Developmental Biology articles

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    1. Developmental Biology

    SVEP1 enables efficient binding of Angiopoietin-2 to the TIE1 receptor, allowing receptor phosphorylation and downstream signaling

    Katharina Uphoff, Melina Hußmann ... Stefan Schulte-Merker
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Cell Biology
    2. Developmental Biology

    Mutations that prevent phosphorylation of the BMP4 prodomain impair proteolytic maturation of homodimers leading to lethality in mice

    Hyung-Seok Kim, Mary L Sanchez ... Jan L Christian
    Phosphorylation of the BMP4 prodomain is required for proteolytic activation of BMP4 homodimers, but not BMP4/7 heterodimers.
    1. Developmental Biology

    Evolution of lateralized gustation in nematodes

    Marisa Mackie, Vivian Vy Le ... Ray L Hong
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Developmental Biology

    Integrated transcriptomic analysis of human induced pluripotent stem cell-derived osteogenic differentiation reveals a regulatory role of KLF16

    Ying Ru, Meng Ma ... Meng Wu
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Developmental Biology

    An increase in reactive oxygen species underlies neonatal cerebellum repair

    Anna Pakula, Salsabiel El Nagar ... Alexandra L Joyner
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Developmental Biology

    Comparative analysis of the syncytiotrophoblast in placenta tissue and trophoblast organoids using snRNA sequencing

    Madeline M Keenen, Liheng Yang ... Carolyn B Coyne
    Trophoblast organoids recapitulate syncytiotrophoblast nuclear heterogeneity and reveal environment-dependent gene regulation critical for placental hormone production and differentiation.
    1. Developmental Biology

    Progressive mural cell deficiencies across the lifespan in a foxf2 model of Cerebral Small Vessel Disease

    Merry Faye E Graff, Emma EM Heeg, Sarah J Childs
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Compelling
    1. Developmental Biology
    2. Neuroscience

    Commissureless acts as a substrate adapter in a conserved Nedd4 E3 ubiquitin ligase pathway to promote axon growth across the midline

    Kelly G Sullivan, Greg J Bashaw
    Commissureless works with the Nedd4 E3 ubiquitin ligase to transiently degrade the Robo1 receptor to allow commissural axons to cross the midline.
    Version of Record
    Research Article
    • Fundamental
    • Compelling
    • Convincing
    1. Cell Biology
    2. Developmental Biology

    Cross-species insemination reveals mouse sperm ability to enter and cross the fish micropyle

    Suma Garibova, Eva Stickler ... Matteo A Avella
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Developmental Biology

    Stimulatory and inhibitory G-protein signaling relays drive cAMP accumulation for timely metamorphosis in the chordate Ciona

    Akiko Hozumi, Nozomu M Totsuka ... Yasunori Sasakura
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
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