Browse our latest Developmental Biology articles

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    1. Developmental Biology

    Genome-wide discovery of cis-regulatory elements in a large genome

    Gillian Forbes, Emilia Skafida ... Mathilde Paris
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Developmental Biology

    Primordial cardiomyocytes orchestrate myocardial morphogenesis and vascularization but are dispensable for regeneration

    Jisheng Sun, Lu Chen, Jinhu Wang
    Primordial cardiomyocytes play an essential role in myocardial morphogenesis and coronary vascularization, but not in adult zebrafish heart regeneration.
    1. Developmental Biology

    Trpv4 links environmental temperature to testicular differentiation in hermaphroditic ricefield eel

    Zhi Yang, Tingting Luo ... Yuhua Sun
    Warm temperature promotes gonadal transformation of ricefield eel by inducing the expression of male pathway genes in ovaries via the Trpv4-pStat3-Kdm6b-Dmrt1 axis.
    1. Developmental Biology
    2. Neuroscience

    Complementary vertebrate Wac models exhibit phenotypes relevant to DeSanto-Shinawi Syndrome

    Kang-Han Lee, April M Stafford ... Daniel Vogt
    Two distinct vertebrate models were generated and phenotyped to study DESSH syndrome caused by the Wac gene.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Nutrient Microenvironments Reprogram Pigment Epithelium Metabolism and Phenotype

    Rayne R Lim, Emily Zhao ... Jennifer R Chao
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Developmental Biology
    2. Genetics and Genomics

    Multiple molecular pathways to longevity with opposing gene expression programs defining distinct aging strategies in Caenorhabditis elegans

    Zenith D Rudich, Jiaxi Guan ... Jeremy M Van Raamsdonk
    Comparing gene expression across a panel of nine long-lived mutants in a single study reveals that these mutants utilize both common and unique genetic strategies to achieve long life.
    1. Developmental Biology

    Tatton-Brown-Rahman Syndrome-associated DNMT3A mutations de-repress cortical interneuron differentiation to disrupt neuronal network function

    Gareth Chapman, Julianna J Determan ... Kristen L Kroll
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Developmental Biology
    2. Evolutionary Biology

    Latent gene network expression underlies partial re-evolution of a polyphenic trait in the worker caste of ants

    Angelly Vasquez-Correa, Johanna Arnet ... Ehab Abouheif
    Latent developmental potential facilitates trait re-evolution with novel phenotypic patterns, adding a new perspective to understanding of the origins of novel traits in evolutionary and developmental biology.
    1. Developmental Biology

    Molecular mechanisms underlying the prepupal-instar-forming metamorphosis in black soldier fly (Hermetia illucens)

    Lingtao Zhang, Masami Shimoda, Chieka Minakuchi
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    Nucleation-dependent propagation of Polycomb modifications emerges during the Drosophila maternal to zygotic transition

    Natalie Gonzaga-Saavedra, Eleanor A Degen ... Shelby A Blythe
    Epigenomics and quantitative imaging are used to investigate the re-establishment of histone modifications associated with the Polycomb group of epigenetic regulators during the Drosophila maternal-to-zygotic transition.
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