Browse our latest Developmental Biology articles

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    1. Developmental Biology
    2. Computational and Systems Biology

    Single-cell spatial mapping reveals reproducible cell type organization and spatially-dependent gene expression in gastruloids

    Catherine G Triandafillou, Pranav Sompalle ... Arjun Raj
    Revised
    Reviewed Preprint v2
    Updated
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    1. Developmental Biology

    Junctional β-Catenin Stabilization Links Wnt Signaling and Force Generation

    Agimaa Otgonbaatar, Sujithra Shankar ... Nicholas S Tolwinski
    Not revised
    Reviewed Preprint v1
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    1. Developmental Biology

    MATR3 is essential for oocyte growth and maturation quality through a dual molecular mechanism

    Yibing Bao, Zhenzi Zuo ... Chao Wang
    Revised
    Reviewed Preprint v2
    Updated
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    1. Developmental Biology

    Comparative single-cell transcriptomic roadmap of mammalian fetal ovarian development

    Yifei Fang, Shiyao Han ... Jingyue Ellie Duan
    Not revised
    Reviewed Preprint v1
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    • Incomplete
    1. Developmental Biology

    Single-cell characterization of anterior segment development in the mouse reveals the cell types, pathways, and signals driving formation of the trabecular meshwork and Schlemm’s canal

    Revathi Balasubramanian, Nicholas Tolman ... Simon WM John
    High-resolution single-cell transcriptomics reveals the molecular programs and signaling networks driving Schlemm's canal and trabecular meshwork development, establishing a foundation for understanding glaucoma pathogenesis.
    1. Computational and Systems Biology
    2. Developmental Biology

    Quantitative computerized analysis demonstrates strongly compartmentalized tissue deformation patterns underlying mammalian heart tube formation

    Morena Raiola, Miquel Sendra Sendra ... Miguel Torres
    A computational pipeline leverages mammalian heart development videos to extract tissue deformation patterns and generate a virtual fate map tool that provides new insights into cardiac morphogenesis.
    1. Developmental Biology

    A genetic screen reveals dosage-sensitive effects of ASD genes and identifies domino as a regulator of synaptic and behavioral phenotypes

    Ellen Stirtz, Zachary B Madaj ... Adelheid Lempradl
    Not revised
    Reviewed Preprint v1
    • Important
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    • Incomplete
    1. Developmental Biology
    2. Genetics and Genomics

    Flexible and high-throughput simultaneous profiling of gene expression and chromatin accessibility in single cells

    Volker Soltys, Moritz A Peters ... Yingguang Frank Chan
    A single-cell multiomic technique measuring both transcription and chromatin accessibility in the same cell.
    1. Developmental Biology

    Paternal over- and under-nutrition programme fetal and placental development in a sex-specific manner in mice

    Hannah L Morgan, Nader Eid ... Adam J Watkins
    Poor paternal nutrition at the time of conception shapes post-fertilisation developmental trajectory, fetal growth, and placental dynamics.
    1. Developmental Biology

    Gcn5 – mTORC1 – TFEB signalling axis mediated control of autophagy regulates Drosophila blood cell homeostasis

    Arjun Aji Reeja, Mincy Kunjumon ... Rohan Jayant Khadilkar
    Revised
    Reviewed Preprint v2
    Updated
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