Browse our latest Developmental Biology articles

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    1. Developmental Biology

    Paternal over- and under-nutrition program fetal and placental development in a sex-specific manner in mice

    Hannah L Morgan, Nader Eid ... Adam J Watkins
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Developmental Biology

    Mural cells protect the adult brain from hemorrhage but do not control the blood–brain barrier in developing zebrafish

    Oguzhan F Baltaci, Andrea Usseglio Gaudi ... Benjamin M Hogan
    Pericytes regulate cerebrovascular development, while vascular smooth muscle cells prevent hemorrhage and blood–brain barrier breakdown at vascular hotspots in juvenile and adult zebrafish.
    1. Developmental Biology

    Tatton-Brown-Rahman Syndrome-associated DNMT3A mutations de-repress cortical interneuron differentiation to disrupt neuronal network function

    Gareth Chapman, Julianna J Determan ... Kristen L Kroll
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Developmental Biology

    Endocardial TIE1 synergizes with TIE2 to regulate the atrial internal muscular network assembly

    Kai Ding, Beibei Xu ... Yulong He
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Developmental Biology
    2. Genetics and Genomics

    In situ mutational screening and CRISPR interference define apterous cis-regulatory inputs during compartment boundary formation

    Gustavo Aguilar, Michèle E Sickmann ... Martin Müller
    Early enhancer logic precisely aligns developmental boundaries by integrating HOX, GATA, and signaling inputs, ensuring correct tissue patterning and preventing mirror-image duplications in the developing wing.
    1. Computational and Systems Biology
    2. Developmental Biology

    A quantitative pipeline for whole-mount deep imaging and analysis of multi-layered organoids across scales

    Alice Gros, Jules Vanaret ... Sham Tlili
    The Tapenade pipeline enables single-cell, whole-mount 3D quantification in dense multilayer organoids, linking spatial gene co-expression and nuclear deformation to emerging tissue-scale organization.
    1. Developmental Biology
    2. Immunology and Inflammation

    Mitochondrial metabolic remodeling drives innate immune activation in Drosophila hemocytes

    Daewon Lee, Ferdinand Koranteng ... Jiwon Shim
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Developmental Biology

    Single-cell transcriptomics-informed induced pluripotent stem cells differentiation to tenogenic lineage

    Angela Papalamprou, Victoria Yu ... Dmitriy Sheyn
    Exploring the differentiation of iPSC to trunk tenocytes and how the single-cell RNA sequencing and pathway analysis can assist in making it more specific.
    1. Developmental Biology

    Peristaltic contractions drive gut anisotropic growth through collective cell rearrangements

    Koji Kawamura, Yoshiko Takahashi, Masafumi Inaba
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete