Browse our latest Developmental Biology articles

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    1. Developmental Biology

    Svep1 orchestrates distal airway patterning and alveolar differentiation in murine lung development

    Nicole Foxworth, Julie Wells ... Maria Loscertales
    Genetic and functional analyses identify SVEP1 as an extracellular matrix regulator that coordinates airway branching, smooth muscle differentiation, and alveolar maturation during lung development.
    1. Developmental Biology
    2. Neuroscience

    Neurotrophin-3 produced by motor neurons non-cell autonomously regulates the development of pre-motor interneurons in the developing spinal cord

    Andrea Angla-Navarro, Ana Dominguez Bajo ... Frédéric Clotman
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Cell Biology
    2. Developmental Biology

    Krüppel Regulates Cell Cycle Exit and Limits Adult Neurogenesis of Mushroom Body Neural Progenitors in Drosophila

    Dongni Shao Chen, Jin Man ... Yuu Kimata
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Developmental Biology

    Genome-wide discovery of cis-regulatory elements in a large genome

    Gillian Forbes, Emilia Skafida ... Mathilde Paris
    Integrating genome-wide maps of chromatin accessibility and sequence conservation provides an accessible low-cost approach for identifying cis-regulatory elements in large genomes, validated in the emerging model Parhyale.
    1. Developmental Biology

    Bidirectional redistribution of actomyosin drives epithelial invagination in ascidian siphon tube morphogenesis

    Jinghan Qiao, Pengyu Yu ... Bo Dong
    Bidirectional relocation of actomyosin as a novel mechanism drives invagination in developing organs.
    1. Genetics and Genomics
    2. Developmental Biology
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    Lifestyle, Environment and Epigenetic Inheritance: A Collection of Articles

    Edited by Wei Yan
    eLife publishes research on the mechanisms and biological significance of environmentally driven epigenetic inheritance.
    1. Cell Biology
    2. Developmental Biology

    Zinc is a key regulator of the sperm-specific K+ channel (Slo3) function

    Rizki Tsari Andriani, Tanadet Pipatpolkai ... Takafumi Kawai
    Intracellular zinc dynamically changes during sperm capacitation and regulates Slo3-mediated hyperpolarization, while directly inhibiting Slo3 currents through residues contributing to its slow dissociation.
    1. Computational and Systems Biology
    2. Developmental Biology

    Single-cell spatial mapping reveals reproducible cell type organization and spatially dependent gene expression in gastruloids

    Catherine Triandafillou, Pranav Sompalle ... Arjun Raj
    Detailed, single-cell spatial gene expression across multiple gastruloids highlights macro-scale organizational consistency, simultaneous with variance in meso-scale patterning.
    1. Developmental Biology

    The livebearers platyfish and swordtails partially regenerate their hearts with persistent scarring

    Vincent Hisler, Lana Rees ... Anna Jaźwińska
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    • Convincing
    1. Developmental Biology

    Cellular basis of accelerated whole-tooth regeneration

    Talha Mubeen, Haowen He ... Jeffrey T Streelman
    Tooth plucking triggers a rapid, coordinated regeneration program in cichlids, accelerating replacement more than threefold through temporally organized epithelial, mesenchymal, immune, vascular, and neural signaling.