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    1. Developmental Biology
    2. Neuroscience

    Dysregulation of mTOR signaling mediates common neurite and migration defects in both idiopathic and 16p11.2 deletion autism neural precursor cells

    Smrithi Prem, Bharati Dev ... Emanuel DiCicco-Bloom
    Alterations in mTOR signaling drive similar dysregulations in the critical mid-fetal neurodevelopmental processes of neurite outgrowth and cell migration in two distinct subsets of autism, idiopathic and 16p11.2 deletion.
    1. Developmental Biology

    Identification and characterization of intermediate states in mammalian neural crest cell epithelial to mesenchymal transition and delamination

    Ruonan Zhao, Emma L. Moore ... Paul A. Trainor
    1. Developmental Biology

    Repulsive Sema3E-Plexin-D1 signaling coordinates both axonal extension and steering via activating an autoregulatory factor, Mtss1

    Namsuk Kim, Yan Li ... Won-Jong Oh
    Repulsive guidance cues enhance a dual-functioning axonal trafficking facilitator, allowing navigating axons to ensure proper pathfinding by coordinating positive extension and negative steering during nervous system development.
    1. Developmental Biology
    2. Neuroscience

    Semaphorin7A patterns neural circuitry in the lateral line of the zebrafish

    Agnik Dasgupta, Caleb C. Reagor ... A. J. Hudspeth
    1. Developmental Biology
    2. Neuroscience

    The ketone body β-hydroxybutyrate rescues neurodevelopmental deficits in the GABAergic system of daf-18/PTEN Caenorhabditis elegans mutants

    Sebastián Giunti, María Gabriela Blanco ... Diego Rayes
    1. Developmental Biology

    Essential Function of Transmembrane Transcription Factor MYRF in Promoting Transcription of miRNA lin-4 during C. elegans Development

    Zhimin Xu, Zhao Wang ... Yingchuan B. Qi
    1. Developmental Biology
    2. Genetics and Genomics

    Inhibitory G proteins play multiple roles to polarize sensory hair cell morphogenesis

    Amandine Jarysta, Abigail L.D. Tadenev ... Basile Tarchini
    1. Developmental Biology
    2. Genetics and Genomics

    Disruption in CYLC1 leads to acrosome detachment, sperm head deformity, and male in/subfertility in humans and mice

    Hui-Juan Jin, Yong Fan ... Su-Ren Chen
    Cylicin-1, a perinuclear theca protein, is critical for acrosome attachment and sperm head morphology.
    1. Developmental Biology
    2. Evolutionary Biology

    ROCK and the actomyosin network control biomineral growth and morphology during sea urchin skeletogenesis

    Eman Hijaze, Tsvia Gildor ... Smadar Ben-Tabou de-Leon
    ROCK and the actomyosin network are essential for multiple aspects of sea urchin skeletogenesis, suggesting an independent deployment of these factors in biomineralization across Eukaryotes.
    1. Developmental Biology

    The E3 ubiquitin ligase RNF220 maintains hindbrain Hox expression patterns through regulation of WDR5 stability

    Huishan Wang, Xingyan Liu ... Pengcheng Ma
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