Nicole Foxworth, Julie Wells ... Maria Loscertales
Genetic and functional analyses identify SVEP1 as an extracellular matrix regulator that coordinates airway branching, smooth muscle differentiation, and alveolar maturation during lung development.
Integrating genome-wide maps of chromatin accessibility and sequence conservation provides an accessible low-cost approach for identifying cis-regulatory elements in large genomes, validated in the emerging model Parhyale.
Intracellular zinc dynamically changes during sperm capacitation and regulates Slo3-mediated hyperpolarization, while directly inhibiting Slo3 currents through residues contributing to its slow dissociation.
Tooth plucking triggers a rapid, coordinated regeneration program in cichlids, accelerating replacement more than threefold through temporally organized epithelial, mesenchymal, immune, vascular, and neural signaling.