Niklas Krick, Jacob J Davies ... Matthias Landgraf
Within the locomotor network of the Drosophila embryo, connected elements, from premotor interneuron to muscle, respond differentially to a critical period perturbation, suggesting a sequence of adjustment.
The activity of Dcp-1, one of Drosophila executioner caspases, is selectively regulated by the autophagy–Bruce axis, which enables distinct non–lethal functions for promoting tissue growth independent of cell death.
Nicole Foxworth, Julie Wells ... Maria Loscertales
Genetic and functional analyses identify SVEP1 as an extracellular matrix regulator that coordinates airway branching, smooth muscle differentiation, and alveolar maturation during lung development.
Integrating genome-wide maps of chromatin accessibility and sequence conservation provides an accessible low-cost approach for identifying cis-regulatory elements in large genomes, validated in the emerging model Parhyale.