Endogenous BMP2/7 and BMP4/7 heterodimers form in vivo, and are the predominant functional ligand in many, if not all, tissues of developing mouse embryos.
High resolution in vivo imaging of the zebrafish heart morphogenesis allows quantitative testing of the impact of stretch sensitive channels during outflow tract valve development.
Hairless emerged as an evolutionarily novel regulatory protein that replaced an ancestral paradigm of direct co-repressor recruitment by Suppressor of Hairless, its partner transcription factor in the Notch signaling pathway.
A cell cycle timing mechanism similar to one operating in cultured adult oligodendrocyte progenitor cells controls the growth and patterning of the embryonic chick wing bud.
Size regulation of the otic vesicle, the progenitor of the inner ear, is mediated by mechanical feedback involving fluid influx, hydraulic pressure, and tissue mechanics.
An unprecedented large-scale screen in mice for morphogenetic regulators of tissue development provides major new insights into the roles of Rho GTPases in diverse array of skin developmental processes.
