Casein kinase Iε phosphorylation has opposite effects on the stability of the core planar polarity proteins Strabismus and Dishevelled, leading to their sorting to opposite cell ends.
The fish gill, an ever-growing organ with fast turnover rate, displays dedicated stem-cell populations for growth and homeostasis that are interchangeable upon external challenges.
Neural stem cells dynamically polarize through the stepwise activity of polarized cortical targeting and cortical flows that coalescence discontinuous cortical patches into an organized cap structure.
Genetic studies reveal a role for Yap1 in lymphatic endothelial progenitor cell sprouting and proliferation during early zebrafish lymphatic vascular development.
Human skeletal muscle progenitors and motor neurons self-organize in three-dimensional co-culture to form functional neuromuscular junctions that developmentally mature from the embryonic to the adult state.
The Hox transcription factor Ultrabithorax (Ubx) represses alternative gene programs during lineage development by lineage-specific Polycomb protein complex retention at Ubx-targeted chromatin sites.
