Browse our latest Developmental Biology articles

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    1. Cell Biology
    2. Developmental Biology

    Fat2 polarizes the WAVE complex in trans to align cell protrusions for collective migration

    Audrey Miller Williams, Seth Donoughe ... Sally Horne-Badovinac
    1. Developmental Biology
    2. Genetics and Genomics

    Fibroblast-derived Hgf controls recruitment and expansion of muscle during morphogenesis of the mammalian diaphragm

    Elizabeth M Sefton, Mirialys Gallardo ... Gabrielle Kardon
    HGF derived from fibroblasts is critical for complete muscularization of the mammalian diaphragm, and loss-of-function experiments reveal that partial muscularization of the diaphragm is not sufficient to cause congenital diaphragmatic hernias.
    1. Developmental Biology
    2. Neuroscience

    Photoreceptors generate neuronal diversity in their target field through a Hedgehog morphogen gradient in Drosophila

    Matthew P Bostock, Anadika R Prasad ... Vilaiwan M Fernandes
    Photoreceptors diversify their target field at long range through a graded signal.
    1. Developmental Biology
    2. Neuroscience

    Differentiation signals from glia are fine-tuned to set neuronal numbers during development

    Anadika R Prasad, Inês Lago-Baldaia ... Vilaiwan M Fernandes
    Extrinsic signals establish an invariant and stereotyped pattern of neuronal differentiation and programmed cell death in the Drosophila visual system.
    1. Developmental Biology

    Regulation of Nodal signaling propagation by receptor interactions and positive feedback

    Hannes Preiß, Anna C Kögler ... Patrick Müller
    1. Cell Biology
    2. Developmental Biology

    Live-cell imaging in human colonic monolayers reveals ERK waves limit the stem cell compartment to maintain epithelial homeostasis

    Kelvin W Pond, Julia M Morris ... Andrew L Paek
    Human colonic organoid monolayers self organize into regularly spaced stem and differentiated cell compartments, which are maintained by waves of ERK activity originating from extruded/dying cells.
    1. Developmental Biology
    2. Genetics and Genomics

    Variable paralog expression underlies phenotype variation

    Raisa Bailon-Zambrano, Juliana Sucharov ... James Nichols
    1. Developmental Biology

    Innexin function dictates the spatial relationship between distal somatic cells in the Caenorhabditis elegans gonad without impacting the germline stem cell pool

    Theadora Tolkin, Ariz Mohammad ... David Greenstein
    Somatic gonad architecture is regulated by innexin function, but sheath cell position does not determine germ cell exit from the stem cell pool.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    The C. elegans gonadal sheath Sh1 cells extend asymmetrically over a differentiating germ cell population in the proliferative zone

    Xin Li, Noor Singh ... Kacy Lynn Gordon
    As Caenorhabditis elegans adult hermaphrodite germ cells leave the stem cell niche, they associate with a pair of somatic gonad cells that were thought to be symmetrical, but that actually take on dramatically different positions in the organ.