Exploring the differentiation of iPSC to trunk tenocytes and how the single-cell RNA sequencing and pathway analysis can assist in making it more specific.
William Salvidge, Chris Brimson ... Chris Thompson
Experiments and mathematical modelling show cell fate in Dictyostelium discoideum partly depends on cell-cycle phase, but also on stochastic gene-expression variability which enhances robustness of developmental responses to cell-cycle perturbation.
Drosophila female germline tumors mutant for bam or bgcn mimic the stem cell niche to inhibit the differentiation of neighboring wild-type germline stem cells.
The Drosophila ryanodine receptor plays a conserved role in setting functional and structural muscle properties, regulates embryonic muscle development and could be used to assess the impact of human RYR1 mutations.
