Browse our latest Developmental Biology articles

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    1. Developmental Biology
    2. Genetics and Genomics

    Flexible and high-throughput simultaneous profiling of gene expression and chromatin accessibility in single cells

    Volker Soltys, Moritz Peters ... Yingguang Frank Chan
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Developmental Biology

    Genetic network shaping Kenyon cell identity and function in Drosophila mushroom bodies

    Pei-Chi Chung, Kai-Yuan Ku ... Hung-Hsiang Yu
    The genetic network of BTB zinc finger transcription factors and Eip93F is crucial for Kenyon cell identity regulation and neuronal function acquisition in the construction of Drosophila mushroom bodies.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    Massively parallel reporter assay for mapping gene-specific regulatory regions at single-nucleotide resolution

    Alastair J Tulloch, Ryan Nicholas Delgado ... Constance L Cepko
    Integrated locus-specific and mutational MPRAs reveal regulatory modules and nucleotide determinants governing cell type-specific gene expression, providing a scalable framework for mapping cis-regulatory architecture.
    1. Developmental Biology

    Cytoplasmatic polyadenylation of mRNA by TENT5A is critical for enamel mineralization

    Goretti Aranaz-Novaliches, Olga Gewartowska ... Jan Prochazka
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Developmental Biology

    Oocyte Development: The discovery of the mammalian fusome

    Michael Buszczak, Anirban Dasgupta
    The presence of an organelle called the fusome in species as diverse as Drosophila and mammals indicates an ancient, conserved programme of germ cell development.
    Version of Record
    Insight
    1. Developmental Biology
    2. Neuroscience

    Cell cycle-dependent cues regulate temporal patterning of the Drosophila central brain neural stem cells

    Gonzalo N Morales Chaya, Mubarak Hussain Syed
    Intrinsic cell cycle progression governs developmental time in neural stem cells by regulating temporal gene transitions that generate neural diversity.
    1. Developmental Biology

    Paternal over- and under-nutrition program fetal and placental development in a sex-specific manner in mice

    Hannah L Morgan, Nader Eid ... Adam J Watkins
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Developmental Biology

    Trehalose metabolism regulates transcriptional control of muscle development in lepidopteran insects

    Sharada Mohite, Tanaji Devkate ... Rakesh Shamsunder Joshi
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Cell Biology
    2. Developmental Biology

    BICC1 interacts with PKD1 and PKD2 to drive cystogenesis in ADPKD

    Uyen Tran, Andrew J Streets ... Oliver Wessely
    The RNA-binding protein BICC1 can act as a genetic disease modifier for kidney cyst formation, potentially explaining the high variability of disease onset and severity in autosomal-dominant polycystic kidney disease patients.
    1. Developmental Biology
    2. Genetics and Genomics

    Equity, Diversity and Inclusion: Four women whose pioneering contributions to science have been largely overlooked

    Lisa M Thomann, Julie Batut
    Ethel Browne Harvey, Hilde Pröscholdt Mangold, Ida Henrietta Hyde and Marthe Gautier all made important contributions to developmental biology, but their names are largely absent from histories of science.