During zebrafish embryogenesis, dact1 and dact2 are necessary for axis lengthening and craniofacial morphogenesis, and the protease capn8 is misexpressed in dact1/2 mutants.
An analysis of vestibular projection neurons lacking their motor neuron partners resolves outstanding controversies for whether and how motor neurons shape vestibulo-ocular reflex circuit assembly.
A member of the Inhibitor of DNA-binding (Id) gene family, best known as negative regulators of tissue-specific master regulatory bHLH transcription factors, also suppresses non-apoptotic caspase activities.
New research shows that the neural circuit responsible for stabilising gaze can develop in the absence of motor neurons, contrary to a long-standing model in the field.