Browse our latest Evolutionary Biology articles

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    1. Evolutionary Biology

    Heterozygote advantage cannot explain MHC diversity, but MHC diversity can explain heterozygote advantage

    Joshua L Cherry
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Computational and Systems Biology
    2. Evolutionary Biology

    Importance of higher-order epistasis in protein sequence-function relationships

    Palash Sethi, Juannan Zhou
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Evolutionary Biology

    Forecasting protein evolution by integrating birth-death population models with structurally constrained substitution models

    David Ferreiro, Luis Daniel González-Vázquez ... Miguel Arenas
    Forecasting protein evolution in terms of folding stability using state-of-the-art population genetics and substitution models is feasible in rugged fitness landscapes, whereas forecasting exact amino acid sequences remains more challenging.
    1. Evolutionary Biology

    Parallel HIV-1 fitness landscapes shape viral dynamics in humans and macaques that develop broadly neutralizing antibodies

    Kai S Shimagaki, Rebecca M Lynch, John P Barton
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Evolutionary Biology
    2. Genetics and Genomics

    Fast evolutionary turnover and overlapping variances of sex-biased gene expression patterns defy a simple binary sex classification of somatic tissues

    Chen Xie, Sven Künzel, Diethard Tautz
    Sex-biased gene expression in the body organs evolves rapidly, supporting a mosaic model of maleness and femaleness across tissues and thus challenging binary views of sex characteristics in mammals.
    1. Evolutionary Biology
    2. Physics of Living Systems

    Magnetotactic bacteria optimally navigate natural pore networks

    Alexander P Petroff, Julia Hernandez ... Nina Radchenko-Hannafin
    Diverse magnetotactic bacteria are adapted to the local geomagnetic field and grain size to maximize their swimming speed through the pore space.
    1. Evolutionary Biology

    The success of artificial selection for collective composition hinges on initial and target values

    Juhee Lee, Wenying Shou, Hye Jin Park
    Mathematical modeling uncovers how initial and target compositions limit microbial community selection, as inter-community selection clashes with intra-community selection like a rafter battling a waterfall.
    1. Cell Biology
    2. Evolutionary Biology

    Horizontally transferred cell-free chromatin particles function as autonomous ‘satellite genomes’ and vehicles for transposable elements within host cells

    Soumita Banerjee, Soniya Sanjay Shende ... Indraneel Mittra
    Uptake of cell-free chromatin particles released from dying cells and carrying non-coding DNA could redefine mammalian genomics.
    1. Neuroscience
    2. Evolutionary Biology

    Distinct evolutionary trajectories of two integration centres, the central complex and mushroom bodies, across Heliconiini butterflies

    Max S Farnworth, Yi Peng Toh ... Stephen H Montgomery
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Evolutionary Biology
    2. Genetics and Genomics

    Ancient trans-species polymorphism at the Major Histocompatibility Complex in primates

    Alyssa Lyn Fortier, Jonathan K Pritchard
    Trans-species polymorphism at primate Major Histocompatibility Complex genes is old, especially in the 'classical' genes, while rapidly-evolving regions of each gene correspond with proteins' functional domains.
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