Browse our latest Evolutionary Biology articles

Page 4 of 114
    1. Developmental Biology
    2. Evolutionary Biology

    Molecular dynamics of the matrisome across sea anemone life history

    Bruno Gideon Bergheim, Alison G Cole ... Suat Özbek
    Integrated proteomic and single-cell transcriptomic analyses define the Nematostella vectensis matrisome and reveal conserved extracellular matrix functions driving life cycle transitions in this non-bilaterian model.
    1. Cancer Biology
    2. Evolutionary Biology

    Cancer–immune coevolution dictated by antigenic mutation accumulation

    Long Wang, Christo Morison, Weini Huang
    Genetic information in cancer cells reveals the strength of cancer–immune interactions in an individual-based stochastic model, which captures explicit interactions between cancer and effector cells.
    1. Immunology and Inflammation
    2. Evolutionary Biology

    Evolutionary Adaptations of IRG1 Refines Itaconate Synthesis and Mitigates Innate Immunometabolism Trade-offs

    Richard V Szeligowski, Francois Miros ... Hongying Shen
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Evolutionary Biology

    Viral genome sequence datasets display pervasive evidence of strand-specific substitution biases that are best described using non-reversible nucleotide substitution models

    Rita Sianga-Mete, Penelope Hartnady ... Darren P Martin
    Non-reversible nucleotide substitution models best describe strand-specific nucleotide substitution biases of viral genomes.
    1. Evolutionary Biology
    2. Physics of Living Systems

    Adaptations in wing morphology rather than wingbeat kinematics enable flight in small hoverfly species

    Camille Le Roy, Nina Tervelde ... Florian T Muijres
    Small hoverflies compensate for size-related flight challenges through evolutionary changes in wing shape rather than altered wingbeat kinematics.
    1. Evolutionary Biology

    Heterozygote advantage cannot explain MHC diversity, but MHC diversity can explain heterozygote advantage

    Joshua L Cherry
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Computational and Systems Biology
    2. Evolutionary Biology

    Importance of higher-order epistasis in protein sequence-function relationships

    Palash Sethi, Juannan Zhou
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Evolutionary Biology

    Forecasting protein evolution by integrating birth-death population models with structurally constrained substitution models

    David Ferreiro, Luis Daniel González-Vázquez ... Miguel Arenas
    Forecasting protein evolution in terms of folding stability using state-of-the-art population genetics and substitution models is feasible in rugged fitness landscapes, whereas forecasting exact amino acid sequences remains more challenging.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Fast evolutionary turnover and overlapping variances of sex-biased gene expression patterns defy a simple binary sex classification of somatic tissues

    Chen Xie, Sven Künzel, Diethard Tautz
    Sex-biased gene expression in the body organs evolves rapidly, supporting a mosaic model of maleness and femaleness across tissues and thus challenging binary views of sex characteristics in mammals.