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Page 2 of 29
Genetic diversity of CHC22 clathrin impacts its function in glucose metabolism
Matteo Fumagalli et al.
Natural selection shaped CHC22 clathrin genetic variation in humans with different diets and potentially influenced the human insulin response.
Disentangling strictly self-serving mutations from win-win mutations in a mutualistic microbial community
Samuel Frederick Mock Hart et al.
Whereas partner-serving phenotype is intuitively quantified as benefit release rate, molecular genetics revealed an example where this thinking fails, motivating a more general metric.
Sterol transfer by atypical cholesterol-binding NPC2 proteins in coral-algal symbiosis
Elizabeth Ann Hambleton et al.
Diversification of a conserved cholesterol binder drives functional replacement of cholesterol with symbiont-produced sterols in corals living in nutrient-poor environments.
Compound-V formations in shorebird flocks
Aaron J Corcoran, Tyson L Hedrick
Shorebird flocks fly in a formation that re-creates the neighbor positioning relationship of a V-formation in cluster flocks of more than 1000 birds.
The genomes of polyextremophilic Cyanidiales contain 1% horizontally transferred genes with diverse adaptive functions
Alessandro W Rossoni et al.
Biochemistry and Chemical Biology
'Palaeoshellomics’ reveals the use of freshwater mother-of-pearl in prehistory
Jorune Sakalauskaite et al.
Ancient proteomes from tiny shell ornaments were successfully characterised for the first time, showing the unexpected use of mother-of-pearl from local riverine molluscs in both coastal and inland prehistoric sites.
A generally conserved response to hypoxia in iPSC-derived cardiomyocytes from humans and chimpanzees
Michelle C Ward, Yoav Gilad
Evolutionarily conserved hypoxic stress response genes are depleted for association with expression quantitative trait loci.
Stem Cells: Getting to the heart of cardiovascular evolution in humans
Alex Pollen, Bryan J Pavlovic
Differences in the response of cardiomyocytes to oxygen deprivation in humans and chimpanzees may explain why humans are more prone to certain heart diseases.
Genetics and Genomics
Independent amylase gene copy number bursts correlate with dietary preferences in mammals
Petar Pajic et al.
Comprehensive analyses of amylase duplications and salivary activity across mammals underscore the importance of recurrent copy number variation as a flexible and rapid evolutionary mechanism.
Genetics and Genomics
Evolution: Of starch and spit
Mareike C Janiak
Animals living alongside humans have multiple copies of the gene for alpha-amylase, the enzyme that breaks down starchy foods, and high levels of this protein in their saliva.
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