Browse our latest Microbiology and Infectious Disease articles

Page 154 of 177
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Cell-wall remodeling drives engulfment during Bacillus subtilis sporulation

    Nikola Ojkic, Javier López-Garrido ... Robert G Endres
    Imaging experiments and simulations reveal that the biophysical mechanism for force generation needed to engulf a forespore is based on coordinated cell wall synthesis and degradation.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    A Herpesviral induction of RAE-1 NKG2D ligand expression occurs through release of HDAC mediated repression

    Trever T Greene, Maria Tokuyama ... Laurent Coscoy
    Viral infection can induce NKG2D ligand expression through the action of virally encoded histone deacetylase (HDAC) inhibitors, which release HDAC mediated repression of NKG2D ligands.
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    Malaria parasite CelTOS targets the inner leaflet of cell membranes for pore-dependent disruption

    John R Jimah, Nichole D Salinas ... Niraj H Tolia
    The structure, function and mechanism of the malaria vaccine candidate CelTOS reveal a unique pore-forming and membrane-disrupting protein with specificity for the inner leaflet of host and vector cells.
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    A common bacterial metabolite elicits prion-based bypass of glucose repression

    David M Garcia, David Dietrich ... Daniel F Jarosz
    Activity-guided fractionation identifies the first bacterial metabolite that potently induces a prion in nature.
    1. Microbiology and Infectious Disease
    2. Plant Biology

    A complete toolset for the study of Ustilago bromivora and Brachypodium sp. as a fungal-temperate grass pathosystem

    Franziska Rabe, Jason Bosch ... Armin Djamei
    The establishment of Ustilago bromivora and Brachypodium as a biotrophic model system provides the foundation for studying new aspects of plant-pathogen interactions and for answering questions about fungal sex and speciation.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Viral RNA switch mediates the dynamic control of flavivirus replicase recruitment by genome cyclization

    Zhong-Yu Liu, Xiao-Feng Li ... Cheng-Feng Qin
    A conserved element in the flavivirus genomic 5′ terminus switches its conformation in response to long-range RNA interactions, and thereby regulates the dynamic recruitment of viral replicase for efficient viral RNA replication.
    1. Microbiology and Infectious Disease

    Factors essential for L,D-transpeptidase-mediated peptidoglycan cross-linking and β-lactam resistance in Escherichia coli

    Jean-Emmanuel Hugonnet, Dominique Mengin-Lecreulx ... Michel Arthur
    Production of the L,D-transpeptidase YcbB and elevated synthesis of the (p)ppGpp alarmone reveals a new mode of peptidoglycan polymerization that bypasses the D,D-transpeptidase activity of PBPs and leads to broad-spectrum β-lactam resistance in Escherichia coli.
    1. Microbiology and Infectious Disease

    Temporal proteomic analysis of HIV infection reveals remodelling of the host phosphoproteome by lentiviral Vif variants

    Edward JD Greenwood, Nicholas J Matheson ... Paul J Lehner
    A comprehensive whole cell proteomic map describing expression time courses of >6,500 viral and cellular proteins during HIV infection identifies Vif-dependent antagonism of key cellular phosphatase PP2A.
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    Bacterial flagellar capping proteins adopt diverse oligomeric states

    Sandra Postel, Daniel Deredge ... Eric J Sundberg
    The first high-resolution structure of a bacterial flagellar cap protein, FliD, reveals new insights into the assembly of bacterial flagella.