Browse our latest Microbiology and Infectious Disease articles

Page 31 of 167
    1. Microbiology and Infectious Disease

    Quantity of SARS-CoV-2 RNA copies exhaled per minute during natural breathing over the course of COVID-19 infection

    Gregory Lane, Guangyu Zhou ... Christina Zelano
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Microbiology and Infectious Disease

    The acetylase activity of Cdu1 regulates bacterial exit from infected cells by protecting Chlamydia effectors from degradation

    Robert J Bastidas, Mateusz Kędzior ... Raphael H Valdivia
    Genetic and biochemical analyses show that Chlamydia protects secreted effectors necessary for its exit from infected cells, preventing them from undergoing ubiquitination and degradation.
    1. Microbiology and Infectious Disease

    Detecting, mapping, and suppressing the spread of a decade-long Pseudomonas aeruginosa nosocomial outbreak with genomics

    William Stribling, Lindsey R. Hall ... Francois Lebreton
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Pharmacologic hyperstabilisation of the HIV-1 capsid lattice induces capsid failure

    KM Rifat Faysal, James C Walsh ... Till Böcking
    The anti-HIV drug lenacapavir breaks the HIV capsid by stabilising regions of low curvature at the expense of maintaining a closed shell, leading to loss of viral DNA synthesis and inhibition of infection.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Response to comment on 'The clinical pharmacology of tafenoquine in the radical cure of Plasmodium vivax malaria: An individual patient data meta-analysis'

    James A Watson, Robert J Commons ... Nicholas J White
    We are writing to respond to comment by Sharma et al, 2024 on our article about the antimalarial drug tafenoquine.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Comment on 'The clinical pharmacology of tafenoquine in the radical cure of Plasmodium vivax malaria: An individual patient data meta-analysis'

    Raman Sharma, Chao Chen ... Panayota Bird
    We are writing to comment on the article by Watson et al., 2022 about the antimalarial drug tafenoquine.
    1. Microbiology and Infectious Disease

    Interplay between acetylation and ubiquitination of imitation switch chromatin remodeler Isw1 confers multidrug resistance in Cryptococcus neoformans

    Yang Meng, Yue Ni ... Chen Ding
    Isw1 acts as a master regulator in modulating the expression of drug-resistance genes, and this regulatory mechanism is dependent on the interaction of Isw1 acetylation and ubiquitination.
    1. Microbiology and Infectious Disease

    Dynamics of macrophage polarization support Salmonella persistence in a whole living organism

    Jade Leiba, Tamara Sipka ... Mai E Nguyen-Chi
    Real-time visualization of Salmonella enterica and polarized macrophage interaction in the living host identifies an anti-inflammatory, pro-regenerative, and motionless macrophage subset as a survival niche during persistent infection.
    1. Microbiology and Infectious Disease

    A dynamic bactofilin cytoskeleton cooperates with an M23 endopeptidase to control bacterial morphogenesis

    Sebastian Pöhl, Manuel Osorio-Valeriano ... Martin Thanbichler
    Analyses of the stalked budding bacterium Hyphomonas neptunium and its spiral-shaped relative Rhodospirillum rubrum reveal a conserved morphogenetic module that controls the establishment of complex bacterial cell shapes.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Ebola virus sequesters IRF3 in viral inclusion bodies to evade host antiviral immunity

    Lin Zhu, Jing Jin ... Cheng Cao
    Ebola virus VP35 protein evades host antiviral immunity by interacting with STING to sequester IRF3 into inclusion bodies and inhibit type I interferon production.