Browse our latest Microbiology and Infectious Disease articles

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    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Long-distance electron transport in multicellular freshwater cable bacteria

    Tingting Yang, Marko S Chavez ... Mohamed Y El-Naggar
    A biophysical approach sheds light on the electron transport physics and electric metabolism of centimeter-long filamentous freshwater cable bacteria.
    1. Microbiology and Infectious Disease

    Hosts manipulate lifestyle switch and pathogenicity heterogeneity of opportunistic pathogens in the single-cell resolution

    Ziguang Wang, Shuai Li ... Wei Liu
    The host acts as an important factor to control the phenotypic heterogeneity of individual symbionts.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Transposon mutagenesis screen in Klebsiella pneumoniae identifies genetic determinants required for growth in human urine and serum

    Jessica Gray, Von Vergel L Torres ... Ian R Henderson
    Klebsiella pneumoniae has specific repertoires of genes required for growth in urine and serum, highlighting new targets for antimicrobial treatments of this important pathogen.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    A single-cell atlas of the miracidium larva of Schistosoma mansoni reveals cell types, developmental pathways, and tissue architecture

    Teresa Attenborough, Kate A Rawlinson ... Matthew Berriman
    A comprehensive description of gene expression and organisation in the cells that constitute the blood fluke larvae responsible for finding and invading its intermediate host.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Released bacterial ATP shapes local and systemic inflammation during abdominal sepsis

    Daniel Spari, Annina Schmid ... Guido Beldi
    Bacteria release ATP as part of their attack in sepsis.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Hyperglycemia induced cathepsin L maturation linked to diabetic comorbidities and COVID-19 mortality

    Qiong He, Miao-Miao Zhao ... Jin-Kui Yang
    High glucose levels promote CTSL maturation and translocation from the endoplasmic reticulum to the lysosome via the ER-Golgi-lysosome axis.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Vaccines: How do adjuvants enhance immune responses?

    Rekha R Rapaka
    By altering which peptide antigens are presented to CD4+ T cells, adjuvants affect the specificity of the immune response.
    Version of Record
    Insight
    1. Microbiology and Infectious Disease

    SPARK regulates AGC kinases central to the Toxoplasma gondii asexual cycle

    Alice L Herneisen, Michelle L Peters ... Sebastian Lourido
    Genetic and proteomic analyses reveal that the SPARK kinase, which is a regulator of key life-cycle transitions in the parasite Toxoplasma gondii, complexes with an elongin-like protein to regulate several important AGC-family kinases.
    1. Microbiology and Infectious Disease

    Metabolic disruption impairs ribosomal protein levels, resulting in enhanced aminoglycoside tolerance

    Rauf Shiraliyev, Mehmet A Orman
    Aminoglycoside tolerance in tricarboxylic acid cycle and electron transport chain mutants does not result from impaired proton motive force and altered drug uptake, but rather from the downregulation of ribosomal proteins, which are primary targets of this drug class.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Hybrid immunity from severe acute respiratory syndrome coronavirus 2 infection and vaccination in Canadian adults: A cohort study

    Patrick E Brown, Sze Hang Fu ... Ab-C Study Collaborators
    Population-level hybrid immunity depends substantially on vaccination coverage, including among those previously infected, and dried blood spot collection serves as a practicable biological surveillance platform for these immune responses.