Browse our latest Microbiology and Infectious Disease articles

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    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    A computational method for predicting the most likely evolutionary trajectories in the stepwise accumulation of resistance mutations

    Ruth Charlotte Eccleston, Emilia Manko ... Nicholas Furnham
    A computational method for predicting evolutionary pathways to antimicrobial resistance, accounting for how epistatic interactions determine trajectories, is described.
    1. Microbiology and Infectious Disease

    Physiological and metabolic insights into the first cultured anaerobic representative of deep-sea Planctomycetes bacteria

    Rikuan Zheng, Chong Wang ... Chaomin Sun
    A deep-sea Planctomycetes bacterium performs a unique budding mode of division and recruits chronic phages for metabolizing nitrogen through the function of auxiliary metabolic genes.
    1. Microbiology and Infectious Disease

    Coordinated regulation of gene expression in Plasmodium female gametocytes by two transcription factors

    Yuho Murata, Tsubasa Nishi ... Masao Yuda
    Sequential expression of two transcription factors that bind to five- and ten-base female-specific cis-acting elements, respectively, promotes differentiation of Plasmodium female gametocytes.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Genetic basis of Arabidopsis thaliana responses to infection by naïve and adapted isolates of turnip mosaic virus

    Anamarija Butkovic, Thomas James Ellis ... Santiago F Elena
    Arabidopsis lines were screened for resistance to TuMV, identifying a region on chromosome 2 linked to necrosis that includes an antiviral gene.
    1. Microbiology and Infectious Disease

    Stumpy forms are the predominant transmissible forms of Trypanosoma brucei

    Jean Marc Tsagmo Ngoune, Parul Sharma ... Brice Rotureau
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    A Vibrio cholerae viral satellite maximizes its spread and inhibits phage by remodeling hijacked phage coat proteins into small capsids

    Caroline M Boyd, Sundharraman Subramanian ... Kimberley D Seed
    A phage parasite encodes an external scaffolding protein to pirate and rearrange phage-encoded coat proteins to more efficiently transfer the phage parasite genome to new hosts and limit phage production.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    The infection-tolerant white-footed deermouse tempers interferon responses to endotoxin in comparison to the mouse and rat

    Ana Milovic, Jonathan V Duong, Alan G Barbour
    Comparing the white-footed deermouse with mice and rats in an inflammation model reveals a means for the observed infection tolerance in this key animal reservoir for several human diseases.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Selection on plastic adherence leads to hyper-multicellular strains and incidental virulence in the budding yeast

    Luke I Ekdahl, Juliana A Salcedo ... Helen A Murphy
    Yeast that were evolved to adhere to plastic surfaces for a few hundred generations became hyper-adherent and more virulent.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Pathogen Evolution: Exploring accidental virulence

    Daniel FQ Smith
    Experimentally evolving yeast to adhere better to plastic led to adaptations that increased their ability to cause an infection.
    Version of Record
    Insight
    1. Developmental Biology
    2. Microbiology and Infectious Disease

    Identification of key yeast species and microbe–microbe interactions impacting larval growth of Drosophila in the wild

    Ayumi Mure, Yuki Sugiura ... Yukako Hattori
    The growth of wild Drosophila larvae on fruits is promoted by a yeast releasing essential nutrients extracellularly or by a stable association with a nutrient-providing bacterium established by microbe–microbe interactions.