Browse our latest Microbiology and Infectious Disease articles

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    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Screening the MMV Pathogen Box reveals the mitochondrial bc1-complex as a drug target in mature Toxoplasma gondii bradyzoites

    Deborah Maus, Elyzana Putrianti ... Martin Blume
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing
    1. Developmental Biology
    2. Microbiology and Infectious Disease

    In vitro sexual dimorphism establishment in schistosomes

    Remi Pichon, Magda E Lotkowska ... Gabriel Rinaldi
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Microbiology and Infectious Disease

    Mitochondrial protein FgDML1 impacts DON toxin biosynthesis and cyazofamid sensitivity in Fusarium graminearum by affecting mitochondrial homeostasis

    Chenguang Wang, Xuewei Mao ... Yiping Hou
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    Distinct allosteric remodeling of HIV-1 Env dynamics on virions by gp41-directed antibodies reveals two modes of neutralization

    Wang Xu, Narendra Kumar Gonepudi ... Maolin Lu
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Microbiology and Infectious Disease

    Global transcription factors analyses reveal hierarchy and synergism of regulatory networks and master virulence regulators in Pseudomonas aeruginosa

    Jiadai Huang, Yue Sun ... Xin Deng
    Systematic ChIP-seq profiling of 172 transcription factors in Pseudomonas aeruginosa reveals a hierarchical regulatory architecture governing virulence and establishes a searchable database to guide antimicrobial drug discovery.
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    Epigenetics and chromatin structure regulate var2csa expression and the placental-binding phenotype in Plasmodium falciparum

    Todd Lenz, Madle Sirel ... Ulf Ribacke
    Placenta-binding parasites show that chromatin-based mechanisms regulate placental malaria virulence gene, var2csa, and requires loss of H3K9me3-mediated heterochromatic silencing and 3D nuclear repositioning away from telomeric-repressive clusters.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Synaptotagmin 1 and Synaptotagmin 7 promote MR1-mediated presentation of Mycobacterium tuberculosis antigens

    Se-Jin Kim, Jessie C Peterson ... David Lewinsohn
    Synaptotagmin 1 and Synaptotagmin 7 promote MAIT cell activation during Mycobacterium tuberculosis infection by facilitating MR1 trafficking and antigen presentation.
    1. Microbiology and Infectious Disease

    Gene synteny and translational coupling of sctS and sctT facilitate assembly of the unique helical T3SS export apparatus in Salmonella Typhimurium

    Eunjin Kim, Mirjam Forberger ... Samuel Wagner
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Developmental Biology
    2. Microbiology and Infectious Disease

    Hierarchical cross-linking of a bacterial spore coat Hub protein

    Khira Amara, Catarina Fernandes ... Adriano O Henriques
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Microbiology and Infectious Disease

    A Novel Rapid Host Cell Entry Pathway Determines Intracellular Fate of Staphylococcus aureus

    Marcel Rühling, Fabio Schmelz ... Martin J Fraunholz
    Revised
    Reviewed Preprint v4
    Updated
    • Valuable
    • Solid
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