Queuing theory links multiplicity of infection (MOI) to force of infection (FOI), enabling the estimation of transmission intensity for falciparum malaria (and other infectious diseases) from sparsely sampled surveys.
Katrina M Zinn, Mathew W McLaren ... Matthew J Elrick
Enterovirus D68, a cause of acute flaccid myelitis, disrupts the composition and function of the nuclear pore complex primarily through its 2A protease, which is also toxic to motor neurons.
In an assay focusing on active virus recruitment rather than passive binding, STED microscopy reveals early association of virions to CD151, indicating its early involvement in viral entry platforms formation.