Browse our latest Neuroscience articles

SNAP25 disease mutations within the synaptotagmin interface impair vesicle priming and cause uncontrolled spontaneous release due to enhanced SNARE:SNARE interactions, whereas a mutation within the SNARE-bundle increases the fusion energy barrier.

A novel pan-neuronal antibody has revealed the organization of the nerve net controlling all behavior in the simple cnidarian Hydra.

Cells utilize a membrane-mediated mechanism for mechanosensation, which involves the disruption of lipid rafts and a signal relayed to an ion channel.

A novel network information framework quantifies muscle interactions, characterises their task-relevance, and identifies networks of muscles with similar and complementary functional roles.

Behavioral and neural analyses unravel the angular gyrus’ key role in the prioritization of integrated narratives in memory and the orchestration of theta-frequency reconfigurations underpinning the process of memory integration.

Chimeric RNAs are widely distributed spatiotemporally during human retinal development and have important regulatory functions, such as silencing of CTNNBIP1-CLSTN1 biasing the progenitor cells toward the RPE cell fate at the expense of neural retinal cell fates.

Combining mouse genetic, behavioral, and electrophysiological approaches revealed that a transcription factor is required to shape touch neurons' distal projections in the skin while dispensable for their survival and specification.

The provided framework based on biological models and clinical literature can aid in the optimization of visual cortical prostheses through computational or behavioral simulation experiments, serving as a flexible tool for computational, clinical, and behavioral neuroscientists working on visual neuroprosthetics.