Browse our latest Neuroscience articles

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    1. Neuroscience

    High-throughput mapping of single-neuron projection and molecular features by retrograde barcoded labeling

    Peibo Xu, Jian Peng ... Yuejun Chen
    A multiplexed retrograde virus tracing method captures single-neuron projectome and transcriptome simultaneously.
    1. Medicine
    2. Neuroscience

    Gene–environment pathways to cognitive intelligence and psychotic-like experiences in children

    Junghoon Park, Eunji Lee ... Jiook Cha
    Genetics, socioeconomic conditions, and family and school environments influence cognitive intelligence in children, and this impact may lead to the individual variability of the current and future PLEs.
    1. Neuroscience

    Obesogenic diet induces circuit-specific memory deficits in mice

    Ioannis Bakoyiannis, Eva Gunnel Ducourneau ... Guillaume Ferreira
    Obesogenic diet intake throughout adolescence impairs different types of memory through overactivation of specific hippocampal efferent pathways and targeting these overactive pathways has therapeutic potential.
    1. Neuroscience

    Visual System: Wiring up for controlled flight

    Albert Cardona
    A map showing how neurons that process motion are wired together in the visual system of fruit flies provides new insights into how animals navigate and remain stable when flying.
    Version of Record
    Insight
    1. Neuroscience

    The spatial extent of anatomical connections within the thalamus varies across the cortical hierarchy in humans and macaques

    Amber M. Howell, Shaun Warrington ... Alan Anticevic
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Computational and Systems Biology
    2. Neuroscience

    Endotaxis: A neuromorphic algorithm for mapping, goal-learning, navigation, and patrolling

    Tony Zhang, Matthew Rosenberg ... Markus Meister
    A neural circuit model reveals how biological brains may implement rapid learning and navigation in complex spaces.
    1. Neuroscience

    Computational Neuroscience: Building a mathematical model of the brain

    Frances Skinner
    Automatic leveraging of information in a hippocampal neuron database to generate mathematical models should help foster interactions between experimental and computational neuroscientists.
    Version of Record
    Insight
    1. Developmental Biology
    2. Neuroscience

    Temporal transcriptomic dynamics in developing macaque neocortex

    Longjiang Xu, Zan Yuan ... Xiaozhong Peng
    A useful single-cell resource provides the prenatal macaque different cell types’ gene expression profiles in the parietal cerebral cortex lobe.
    1. Neuroscience

    The mTOR pathway genes MTOR, Rheb, Depdc5, Pten, and Tsc1 have convergent and divergent impacts on cortical neuron development and function

    Lena H Nguyen, Youfen Xu ... Angelique Bordey
    Expression of mTORC1 pathway gene variants in mouse medial prefrontal cortex leads to shared alterations in pyramidal neuron morphology, positioning, and membrane excitability but different changes in excitatory synaptic transmission.
    1. Genetics and Genomics
    2. Neuroscience

    Plasticity of gene expression in the nervous system by exposure to environmental odorants that inhibit HDACs

    Sachiko Haga-Yamanaka, Rogelio Nunez-Flores ... Anandasankar Ray
    Volatile compounds from microbes and food alter epigenetic states by inhibiting histone deacetylases and alter gene expression, slow degeneration in Huntington’s model flies, and slow proliferation of a neuroblastoma cell line.