µGUIDE is a Bayesian framework that leverages simulation-based inference to efficiently estimate posterior distributions of any forward model parameters, allowing for uncertainty quantification and degeneracy detection.
Computational modeling suggests that the BLA is capable of producing the recorded LFP rhythms via interactions of interneuron subtypes, and that those rhythms may be necessary for associative learning.
The amphipathic helix at the C-terminus of Complexin II prevents premature secretion, whereas its N-terminal domain regulates mechanisms which are governed by the forward rate of Ca2+ binding to Synaptotagmin I.
Stimulation of the ipsilateral motor cortex after spinal cord injury activates bilateral motor synergy and restores hindlimb movement, advancing neuroprosthetic strategies for motor recovery.
Juan Carlos Boffi, Brice Bathellier ... Robert Prevedel
Bespoke volumetric calcium imaging, validated with neuropixels recordings, evidence a population code for sound azimuth at the dorsal cortex of the inferior colliculus, with a contribution of noise correlations.
Mice can generate a cognitive map of an environment based on self-motion signals when there is a fixed association between their starting point and the location of their goal.
Katie Morris, Edita Bulovaite ... Mathew H Horrocks
PSD95 supercomplexes maintain long-term stability through gradual subunit replacement, with the slowest turnover in cortical synapses associated with memory storage.
Samyogita Hardikar, Bronte Mckeown ... Jonathan Smallwood
Interactions between attention systems and the default mode network are linked to individual differences in trait and state-level experience and cognition.
John P Grogan, Matthias Raemaekers ... Sanjay G Manohar
Muscarinic antagonism is causally involved in motivation and incentivisation in healthy human participants, partially mediated via preparatory neural signatures, with implications for cholinergic treatment of Parkinson's disease.
