Browse our latest Neuroscience articles

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    1. Neuroscience

    Altered firing output of VIP interneurons and early dysfunctions in CA1 hippocampal circuits in the 3xTg mouse model of Alzheimer’s disease

    Felix Michaud, Ruggiero Francavilla ... Lisa Topolnik
    Early alterations in VIP interneuron activity may contribute to disruptions in CA1 hippocampal circuits and cognitive deficits in the 3xTg mouse model of Alzheimer's disease.
    1. Neuroscience

    Neuroelectrophysiology-compatible electrolytic lesioning

    Iliana E Bray, Stephen E Clarke ... Paul Nuyujukian
    Neuronal loss can be studied by passing electrical current through the same electrodes used for neuron measurement without disrupting recording ability.
    1. Developmental Biology
    2. Neuroscience

    Embryonic origins of forebrain oligodendrocytes revisited by combinatorial genetic fate mapping

    Yuqi Cai, Zhirong Zhao ... Miao He
    Novel genetic fate-mapping strategies enabled re-analysis of cortical oligodendrocytes derived from dorsal pallium, LGE/CGE, and MGE/POA, challenging the canonical view of substantial LGE/CGE contributions and the elimination of MGE/POA-derived populations.
    Version of Record
    Short Report
    • Valuable
    • Convincing
    1. Developmental Biology
    2. Neuroscience

    Lateral/caudal ganglionic eminence makes limited contribution to cortical oligodendrocytes

    Jialin Li, Feihong Yang ... Zhuangzhi Zhang
    The contribution of the lateral/caudal ganglionic eminence to the pool of cortical oligodendrocyte precursor cells is minimal.
    Version of Record
    Short Report
    • Valuable
    • Solid
    1. Neuroscience

    α/β-Hydrolase domain-containing 6 (ABHD6) accelerates the desensitization and deactivation of TARP γ-2-containing AMPA receptors

    Rixu Cong, Huiran Li ... Chen Zhang
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Neuroscience

    Speech-induced suppression and vocal feedback sensitivity in human cortex

    Muge Ozker, Leyao Yu ... Adeen Flinker
    During speech production, auditory regions that show speech-induced suppression are sensitive to changes in auditory feedback, suggesting that suppression may be a key mechanism underlying speech monitoring.
    1. Neuroscience

    Individuals with anxiety and depression use atypical decision strategies in an uncertain world

    Zeming Fang, Meihua Zhao ... Ru-Yuan Zhang
    A model with a mixture of three different decision strategies is developed to characterize several atypical behavioral patterns of individuals with depression and anxiety in an uncertain reward environment.
    1. Neuroscience

    Male cuticular pheromones stimulate removal of the mating plug and promote re-mating through pC1 neurons in Drosophila females

    Minsik Yun, Do-Hyoung Kim ... Young-Joon Kim
    Identification of central neural circuits and sensory pathways underlying social-sexual modulation of sperm ejection in female Drosophila unraveled cryptic mate choice, a mechanism of post-copulatory sexual selection.
    1. Neuroscience

    Mechanical force of uterine occupation enables large vesicle extrusion from proteostressed maternal neurons

    Guoqiang Wang, Ryan J Guasp ... Monica Driscoll
    Large extracellular vesicle extrusion that eliminates neuronal protein aggregates and organelles is potentiated by uterine filling, linking reproductive status to maternal nervous system health, and demonstrating mechanobiology components in exophergenesis.
    1. Neuroscience

    DBT is a metabolic switch for maintenance of proteostasis under proteasomal impairment

    Ran-Der Hwang, YuNing Lu ... Jiou Wang
    A genome-wide screen identifies the BCAA catabolizing enzyme DBT as a master metabolic switch in the regulation of protein quality control when proteasomal activity is impaired.