George A Spirou, Matthew Kersting ... Paul B Manis
Volume electron-microscopic reconstructions of auditory brainstem neurons and their afferent synapses were used to develop a pipeline creating biophysically defined computational models with heterogenous inputs, revealing roles for subthreshold synapses to enhance temporal processing unique features of their dendrites.
Functional assays using zebrafish reveal that various microbial channelrhodopsins, guanylyl cyclase rhodopsin, and photoactivated adenylyl cyclases function as potent optogenetic tools, effectively controlling neural activity and cardiac function in zebrafish.
Animal G-protein-coupled bistable rhodopsins can regulate Gq- and Gi-mediated signaling in a light-dependent manner in neurons and cardiomyocytes, making them useful for analyzing the roles of GPCR signaling in vivo.
Kate Nussenbaum, Rebecca E Martin ... Catherine A Hartley
From middle childhood to early adulthood, the preference to engage with novel choice options remained consistent, but aversion to reward uncertainty increased.
Fernanda Lenita Ribeiro, Ashley York ... Alexander Puckett
The representation of the retina in early visual cortex shows that human brains have diverse functional organizations, raising questions about developmental mechanisms for visual map formation and how reliably these can be described by average templates.
Mahmoud EA Abdellahi, Anne CM Koopman ... Penelope A Lewis
Sound cues that were associated with memories during wake elicit memory reactivations when replayed to human participants during rapid eye movement sleep, those memory reactivations are identifiable by machine learning models that directly relate electroencephalography patterns of wake and sleep.
Lilya Andrianova, Steliana Yanakieva ... Michael T Craig
A combination of anterograde and retrograde anatomical-tracing methods failed to provide evidence of a recently described projection from the anterior cingulate area to the hippocampus.
Lucija Rapan, Sean Froudist-Walsh ... Nicola Palomero-Gallagher
3D atlas of the macaque frontal lobe, based on the novel quantitative parcellation, integrates anatomical, neurochemical, and functional connectivity data.