Allison T Goldstein, Terrence R Stanford, Emilio Salinas
The detection of a salient stimulus triggers a stereotypical oculomotor response, an impulse to look toward it, whose timing and strength are largely independent of behavioral significance and top-down control.
Chronic inhibition of mTORC1 signaling strongly affects the morphology, physiology and output of dopamine neurons leading to impaired dopaminergic function in mice.
Regulation of Cav2.3 Ca2+ channels by membrane-bound β2 subunit splice variants permits long-lasting channel activity even during prolonged and continuous activity in dopamine neurons, with implications for Parkinson's disease pathophysiology.
Nuno Calaim, Florian A Dehmelt ... Christian K Machens
Spiking neural networks become robust to various perturbations of their parameters if their voltages are confined to a lower-dimensional subspace, and both dynamics and robustness can be visualised in this voltage subspace.
Lana Hantzsch, Benjamin Parrell, Caroline A Niziolek
Hearing a single auditory error while speaking causes an adaptive change that corrects for that error the next time we say a word, providing empirical support for current models of speech sensorimotor adaptation and aligning speech with other motor domains.
The membrane nonlinearities of the dendritic arbor of striatal cholinergic interneurons conspire with the spatial distribution of its excitatory inputs to preferentially boost thalamic inputs.
Interhemispheric inhibition can be manipulated by directly and bidirectionally modulating the bilateral sensorimotor excitabilities in a spatially bivariate Brain-Computer Interface-based neurofeedback paradigm.
Selfee, a self-supervised learning approach, is designed to extract comprehensive and discriminative features directly from raw videos of animal behaviors which can be used for in-depth analysis.