Browse our latest Neuroscience articles

Voltage-gated calcium channel delivery to synaptic active zones (AZs) occurs broadly across the population, correlates with AZ size, and is regulated by α2δ, while channel recycling is promoted by new delivery to generate an upper limit on AZ accumulation.

Large-scale mapping of sensory input to the mouse olfactory bulb reveals exceptionally narrow tuning of olfactory receptor input to glomeruli and defines a functional map of glomerular sensitivities that is structured with respect to olfactory chemical space.

Noradrenaline-mediated astrocytic Ca²⁺ signaling in behavior is reduced in awake-behaving tg-ArcSwe Alzheimer's disease transgenic mice.

Invasive electrophysiological recordings from the human brain reveal that different mood levels translate into different brain states that predispose subjects to make risky or safe decisions.

The sour receptor, OTOP1, and related proton channel OTOP3 are steeply activated by extracellular protons while OTOP2 is active over a broad pH range and differences in gating are partly attributed to extracellular domains.

Three-dimensional imaging and automated, brain-wide cell counting yield new insight into the diversity of neurons that connect the brain to the spinal cord and their different sensitivity to spinal cord damage.

In a mouse model of Parkinson's disease, deep brain stimulation of the subthalamic nucleus disrupts movement-related neural activity in parallel with relieving motor symptoms.

Label-free three-photon imaging of whole, uncleared intact organoids generated from Rett syndrome patients show shorter migration distances and slower migration speeds of mutant radially migrating neurons with more tortuous trajectories.

A newly identified pattern of circuit assembly shows connectivity between small groups of neurons born in tight time windows from different stem cells, with outputs from one lineage born before inputs from other lineages.

Excitation of contralesional cortex after stroke suppresses the expression of genes related to plastic neuronal reintegration and accordingly modulates perilesional remodeling and functional network communication at local and global scales.