Browse our latest Neuroscience articles

Drosophila experience two hunger states, one driven by need and the other by pleasure, which arise from unique neural substrates.

A model of early postnatal bacterial meningitis in the mouse demonstrates the transcriptome responses of each of the major meningeal cell types and should prove useful in dissecting the pathophysiology of bacterial meningitis in human infants.

The postinspiratory complex acts as an interface between the swallow pattern generator and the preBötzinger complex to coordinate swallow and breathing.

Motor signs of Parkinson’s disease such as tremor and bradykinesia are independently expressed and exhibit distinct signatures of neural activity that can independently decoded from subthalamic and cortical recordings using interpretable machine learning.

Belly roll, Bero, an Ly6/α-neurotoxin family protein, is identified as a critical modulator of peptidergic interneurons in Drosophila melanogaster, shedding light on genetic regulations of nociceptive escape behaviors and providing a potential target for future studies on pain perception.

Descending inhibition of nociception from the brain has been identified in Drosophila larvae, for the first time in non-mammalian organisms.

In awake behaving rats, cholinergic interneurons in the nucleus accumbens drive dopamine release via nicotinic receptors, boosting motivation to work.

Inter-individual variabilities in nicotine aversion are linked with responses of the interpeduncular nucleus to the drug.

Single-peaked tuning curves found in early sensory areas are more optimized for quick decoding than accuracy, while multi-peaked tuning curves (e.g. grid cells) give higher accuracy but only at longer time scales.

While tau and aging have highly overlapping differential gene expression signatures, they diverge in the affected cell types, with aging having a wide-ranging impact and tau-triggered changes instead polarized to excitatory neurons and glia.