Browse our latest Neuroscience articles

Multiple non-redundant features of non-rapid eye movement sleep are altered in schizophrenia and largely independent of waking electrophysiological abnormalities, supporting the promise of neuropsychiatric disease biomarkers based on a precise dissection of the sleep.

The Kv3.3 potassium channel subunit is necessary and sufficient to permit presynaptic location and accelerated repolarisation of the presynaptic action potential, thereby conserving resources and enhancing accuracy of timing information on transmission at the calyx of Held excitatory synapse.

A new cross-species machine learning-based strategy is applied to find enhancers that specifically label parvalbumin neurons in the mouse and macaque.

Blocking of the function of neurotransmitter receptors by insecticidal peptide toxins resulted in identification of nicotinic acetylcholine receptor subunits through native ligand-binding investigations.

Cohesin is required for the expression of neuronal genes that engage in long chromatin loops, while short-range enhancer-promoter loops can form in the absence of cohesin.

A MRI study of virally infected CNS demonstrates the utility of MRI in detecting the earliest pathological events and studying pathogen-specific T cells at the level of single cell as well as the therapeutic potential of antiviral T cells.

For cerebellar unipolar brush cells that regulate information flow to the vestibulo-cerebellum, dopaminergic modulation by locus coeruleus axons presents a new example of monoaminergic co-release poised to regulate the activity of the cerebellar cortex.

The primate caudal area 47/12 is anatomically and functionally connected with the main nodes of the salience network, supporting the role of the ventrolateral prefrontal cortex in all major attention networks.

Feedback-driven gain modulation provides a mechanism to generate and maintain invariant sensory representations in the presence of contextual changes by dynamically adapting feedforward sensory processing.

Biperiden, but not amisulpride, delays auditory mismatch responses during environmental stability, suggesting a differential sensitivity of auditory statistical learning to muscarinic versus dopaminergic receptor status which could prove useful for developing tests that predict an individual's response to antipsychotic treatment.