Browse our latest Neuroscience articles

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    1. Neuroscience

    Uncertainty-based inference of a common cause for body ownership

    Marie Chancel, H Henrik Ehrsson, Wei Ji Ma
    Behavioral and computational results show that the perception of our body as our own depends on Bayesian probabilistic reasoning that take into account the variations in sensory uncertainty when integrating visual and somatosensory cues.
    1. Neuroscience

    Stability of motor representations after paralysis

    Charles Guan, Tyson Aflalo ... Richard A Andersen
    Neural populations in PPC dynamically represent motor-like and then sensory-like aspects of brain–computer interface finger movements with a representational structure that matches able-bodied individuals.
    1. Neuroscience

    Flexing the principal gradient of the cerebral cortex to suit changing semantic task demands

    Zhiyao Gao, Li Zheng ... Elizabeth Jefferies
    Gradient decomposition of informational connectivity reveals that the principal gradient with the separation of default mode network from sensory-motor systems represents a hallmark of the retrieval of strong conceptual links.
    1. Neuroscience

    Neural signatures of auditory hypersensitivity following acoustic trauma

    Matthew McGill, Ariel E Hight ... Daniel B Polley
    Chronic two-photon calcium imaging, optogenetics, and operant behavioral approaches were leveraged to show that hyperactivity, hyperresponsivity, and hypersynchronization in auditory cortex neural ensembles can account for auditory hypersensitivity following acoustic trauma.
    1. Developmental Biology
    2. Neuroscience

    Plexins promote Hedgehog signaling through their cytoplasmic GAP activity

    Justine M Pinskey, Tyler M Hoard ... Benjamin L Allen
    The plexin family of semaphorin receptors regulate Hedgehog pathway activity via a conserved GAP domain and FYN kinase phosphorylation site in their cytoplasmic domain.
    1. Neuroscience

    Machine learning-assisted fluoroscopy of bladder function in awake mice

    Helene De Bruyn, Nikky Corthout ... Thomas Voets
    A new combined approach using X-ray fluoroscopy and machine learning provides detailed new insights into bladder function in awake, unrestrained mice and unveils important limitations of current approaches to study bladder function.
    1. Developmental Biology
    2. Neuroscience

    EZ Clear for simple, rapid, and robust mouse whole organ clearing

    Chih-Wei Hsu, Juan Cerda III ... Joshua D Wythe
    With three simple steps in 48 hr, EZ Clear effectively renders adult mouse organs optically transparent while simultaneously preserving signal from synthetic and endogenous fluorescent reporters and is compatible with wholemount immunostaining and cryosectioning followed by histological or immunofluorescent staining.
    1. Neuroscience

    Frequency-specific neural signatures of perceptual content and perceptual stability

    Richard Hardstone, Matthew W Flounders ... Biyu J He
    While perceptual content is encoded in non-oscillatory activity in the slow cortical potential (<5 Hz) range, perceptual stability is predominantly influenced by the amplitude fluctuations of alpha (~10 Hz) and beta (~20 Hz) brain oscillations.
    1. Neuroscience

    A novel rhesus macaque model of Huntington’s disease recapitulates key neuropathological changes along with motor and cognitive decline

    Alison R Weiss, William A Liguore ... Jodi L McBride
    mHTT delivery in key cortical and subcortical brain regions leads to hallmark mHTT aggregate formation, gray and white matter degenerative changes, along with motor and cognitive decline in a new macaque model of Huntington's disease.
    1. Neuroscience

    A dopamine-gated learning circuit underpins reproductive state-dependent odor preference in Drosophila females

    Ariane C Boehm, Anja B Friedrich ... Ilona C Grunwald Kadow
    Behavioral and in vivo imaging analysis in the fly suggests that mating-related sensory experience regulates female odor perception and expression of choice behavior through a dopamine-gated learning circuit.