Browse our latest Neuroscience articles

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    1. Neuroscience

    The rapid developmental rise of somatic inhibition disengages hippocampal dynamics from self-motion

    Robin F Dard, Erwan Leprince ... Michel A Picardo
    The first postnatal week ends with the development of perisomatic innervation and with an abrupt switch in the representation of self-motion in the region CA1 of the mouse hippocampus.
    1. Neuroscience

    Visualizing synaptic dopamine efflux with a 2D composite nanofilm

    Chandima Bulumulla, Andrew T Krasley ... Abraham G Beyene
    A technology for measuring release of dopamine simultaneously from hundreds of release sites at the spatial resolution of a synapse is provided.
    1. Neuroscience

    Stress diminishes outcome but enhances response representations during instrumental learning

    Jacqueline Katharina Meier, Bernhard P Staresina, Lars Schwabe
    Decoding of neural outcome and response representations allows dissecting goal-directed and habitual contributions to behaviour and reveals how acute stress biases the instrumental control of behaviour.
    1. Computational and Systems Biology
    2. Neuroscience

    A computational account of why more valuable goals seem to require more effortful actions

    Emmanuelle Bioud, Corentin Tasu, Mathias Pessiglione
    Behavioural evidence and computational analyses suggest that people tend to decline the pursuit of more rewarded goals because they, wrongly, expect them to require more effortful actions.
    1. Neuroscience

    Regulation of presynaptic Ca2+ channel abundance at active zones through a balance of delivery and turnover

    Karen L Cunningham, Chad W Sauvola ... J Troy Littleton
    Voltage-gated calcium channel delivery to synaptic active zones (AZs) occurs broadly across the population, correlates with AZ size, and is regulated by α2δ, while channel recycling is promoted by new delivery to generate an upper limit on AZ accumulation.
    1. Neuroscience

    Mapping odorant sensitivities reveals a sparse but structured representation of olfactory chemical space by sensory input to the mouse olfactory bulb

    Shawn D Burton, Audrey Brown ... Matt Wachowiak
    Large-scale mapping of sensory input to the mouse olfactory bulb reveals exceptionally narrow tuning of olfactory receptor input to glomeruli and defines a functional map of glomerular sensitivities that is structured with respect to olfactory chemical space.
    1. Neuroscience

    Impaired astrocytic Ca2+ signaling in awake-behaving Alzheimer’s disease transgenic mice

    Knut Sindre Åbjørsbråten, Gry HE Syverstad Skaaraas ... Rune Enger
    Noradrenaline-mediated astrocytic Ca2+ signaling in behavior is reduced in awake-behaving tg-ArcSwe Alzheimer's disease transgenic mice.
    1. Computational and Systems Biology
    2. Neuroscience

    Intracerebral mechanisms explaining the impact of incidental feedback on mood state and risky choice

    Romane Cecchi, Fabien Vinckier ... Julien Bastin
    Invasive electrophysiological recordings from the human brain reveal that different mood levels translate into different brain states that predispose subjects to make risky or safe decisions.
    1. Neuroscience
    2. Structural Biology and Molecular Biophysics

    Structural motifs for subtype-specific pH-sensitive gating of vertebrate otopetrin proton channels

    Bochuan Teng, Joshua P Kaplan ... Emily R Liman
    The sour receptor, OTOP1, and related proton channel OTOP3 are steeply activated by extracellular protons while OTOP2 is active over a broad pH range and differences in gating are partly attributed to extracellular domains.
    1. Neuroscience

    Brain-wide analysis of the supraspinal connectome reveals anatomical correlates to functional recovery after spinal injury

    Zimei Wang, Adam Romanski ... Murray G Blackmore
    Three-dimensional imaging and automated, brain-wide cell counting yield new insight into the diversity of neurons that connect the brain to the spinal cord and their different sensitivity to spinal cord damage.