Browse our latest Neuroscience articles

Computational models of large-scale cortical dynamics, integrating gene expression mapping to pattern pharmacological modulation across cortex, capture inter-areal topographies of functional connectivity alterations induced by lysergic acid diethylamide, providing a framework for simulating effects of pharmacology in the human brain.

Spike frequency adaptation provides spiking neural networks with long short-term memory.

Descending interneurons maintain synaptic connectivity and behavioral function despite pruning during metamorphosis, showing that synaptic specificity is established twice at different life stages.

Synaptic resolution analysis of a full olfactory connectome reveals lateralised circuits, convergence of innate and learned pathways, and shows that homologous neurons are highly stereotyped within and across brains.

A combined developmental genetics, electrophysiology, and optical approach identify two distinct and dynamic components of the developing neuronal circuit that relay and interpret thalamic input in primary sensory neocortex.

Increases of extracellular potassium silence capillary pericyte calcium signaling, suggesting a participation of capillary pericytes in the potassium-mediated neurovascular communication.

When all features of conflicting sensory input are task-irrelevant, the brain can still process its sensory information, whereas conflict detection requires that minimally one stimulus feature is task-relevant or associated with a response.

Cell imaging and electrophysiology in the mouse hippocampus reveal a crucial role for the spatiotemporal regulation of mitochondrial dynamics in PV+ interneurons on cell morphology, network activity, and behavior.

During neurotransmitter release, calcium-induced membrane insertion of the C2B domain of Synaptotagmin re-orients the bound SNARE complex which dilates the fusion pore in a mechanical lever action.

Mice exploring a labyrinth freely for the first time learn a complex action sequence after a handful of rewards, exhibiting a learning rate 1000-fold higher than in commonly-used paradigms.