Browse our latest Neuroscience articles

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    1. Neuroscience

    Silencing long ascending propriospinal neurons after spinal cord injury improves hindlimb stepping in the adult rat

    Courtney T Shepard, Amanda M Pocratsky ... David SK Magnuson
    Silencing L2 neurons that project to C6 after a T9 contusion, effectively removing spared axons, results in improved paw placement timing and order, and normalizes speed-dependent changes in swing and stance representing a significant neuroanatomical-functional paradox for spinal cord injury.
    1. Neuroscience

    REST/NRSF drives homeostatic plasticity of inhibitory synapses in a target-dependent fashion

    Cosimo Prestigio, Daniele Ferrante ... Pietro Baldelli
    A combination of electrophysiological, immunocytochemical, and biochemical approaches elucidate the mechanisms by which the transcriptional regulator REST/NRSF rescues neuronal homeostasis by upregulating GABAergic transmission selectively onto excitatory neurons in response to hyperactivity.
    1. Neuroscience

    Pain: Why sex matters

    Josette J Wlaschin, Sangeetha Hareendran, Claire E Le Pichon
    The immune mechanisms underlying hypersensitivity to pain after nerve injury are different in male and female mice.
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    1. Neuroscience

    Motor memories of object dynamics are categorically organized

    Evan Cesanek, Zhaoran Zhang ... J Randall Flanagan
    The motor-relevant properties of the myriad objects with which we interact on a daily basis are encoded in memory using categorical representations, or 'object families'.
    1. Cell Biology
    2. Neuroscience

    Ca2+/CaM binding to CaMKI promotes IMA-3 importin binding and nuclear translocation in sensory neurons to control behavioral adaptation

    Domenica Ippolito, Saurabh Thapliyal, Dominique A Glauser
    Ca2+-dependent nuclear entry of Ca2+/calmodulin-dependent protein kinase-1 in sensory neurons, taking place with a relatively slow kinetics, contributes to couple long-lasting sensory stimulations with signaling in the nucleus over a timescale relevant for sensory history-dependent plasticity.
    1. Evolutionary Biology
    2. Neuroscience

    A small, computationally flexible network produces the phenotypic diversity of song recognition in crickets

    Jan Clemens, Stefan Schöneich ... Berthold Hedwig
    A computational model of the neuronal network that recognizes mating signals reveals network properties that support and constrain behavioral diversity in a species group.
    1. Neuroscience

    Dysfunctions of the paraventricular hypothalamic nucleus induce hypersomnia in mice

    Chang-Rui Chen, Yu-Heng Zhong ... Zhi-Li Huang
    The paraventricular nucleus of the hypothalamus is essential for physiologic arousal and the pathogenesis underlying hypersomnolence disorder.
    1. Neuroscience

    Proximal and distal spinal neurons innervating multiple synergist and antagonist motor pools

    Remi Ronzano, Camille Lancelin ... Marco Beato
    Populations of spinal cord neurons innervate motoneurons controlling local and distant synergist and antagonist muscles.
    1. Neuroscience

    Causal roles of prefrontal cortex during spontaneous perceptual switching are determined by brain state dynamics

    Takamitsu Watanabe
    Prefrontal causal roles in bistable perception are dynamically changing and determined by the brain state to which the whole-brain activity pattern belongs.
    1. Neuroscience

    The Mouse Action Recognition System (MARS) software pipeline for automated analysis of social behaviors in mice

    Cristina Segalin, Jalani Williams ... Ann Kennedy
    The Mouse Action Recognition System is a computational pipeline for automated classification of social behaviors in freely interacting mice, accompanied by a graphical interface for analysis of multimodal neuroscience datasets.