Browse our latest Neuroscience articles

Page 293 of 642
    1. Neuroscience

    Metabolomic profiling reveals a differential role for hippocampal glutathione reductase in infantile memory formation

    Benjamin Bessières, Emmanuel Cruz, Cristina M Alberini
    Hippocampal metabolomic analyses following episodic learning at different ages revealed a critical role for neuronal glutathione reductase activity in long-term infantile memory formation.
    1. Neuroscience

    Circuits for integrating learned and innate valences in the insect brain

    Claire Eschbach, Akira Fushiki ... Marta Zlatic
    Electron-microscopy reconstruction and experimental investigation in Drosophila reveal how adaptive action emerges from the multi-level interactions between the output of the olfactory memory center and the innate olfactory pathway.
    1. Neuroscience

    Subpopulations of neurons in lOFC encode previous and current rewards at time of choice

    David L Hocker, Carlos D Brody ... Christine M Constantinople
    A distinct subpopulation of neurons in the rat orbitofrontal cortex encodes reward history at the time of choice, providing a potential neural substrate by which reward history may influence decisions.
    1. Neuroscience

    Visualizing synaptic plasticity in vivo by large-scale imaging of endogenous AMPA receptors

    Austin R Graves, Richard H Roth ... Richard L Huganir
    A knockin mouse line was made to label endogenous AMPA receptors, enabling direct observation of synaptic plasticity in behaving animals with single-synapse resolution across the entire brain.
    1. Neuroscience
    2. Physics of Living Systems

    Multisensory-motor integration in olfactory navigation of silkmoth, Bombyx mori, using virtual reality system

    Mayu Yamada, Hirono Ohashi ... Shunsuke Shigaki
    Silkmoth utilizes multimodal information to modulate behavior according to the degree of turbulence in the environment, enabling it to efficiently an odor source search.
    1. Medicine
    2. Neuroscience

    scAAVengr, a transcriptome-based pipeline for quantitative ranking of engineered AAVs with single-cell resolution

    Bilge E Öztürk, Molly E Johnson ... Leah C Byrne
    A transcriptome-based pipeline (scAAVengr) quantifies and ranks competing adeno-associated viral vectors in primate retina, and mouse brain, heart, and liver, simultaneously and across all cell types, in the same animal, with single-cell resolution.
    1. Neuroscience

    Live imaging reveals the cellular events downstream of SARM1 activation

    Kwang Woo Ko, Laura Devault ... Aaron DiAntonio
    Axon degeneration occurs via an ordered sequence of events downstream of SARM1 that proceeds from ATP loss, to defects in mitochondrial movement and depolarization, followed by calcium influx, phosphatidylserine externalization, loss of membrane permeability, and ending with catastrophic axonal self-destruction.
    1. Neuroscience

    The decoy SNARE Tomosyn sets tonic versus phasic release properties and is required for homeostatic synaptic plasticity

    Chad W Sauvola, Yulia Akbergenova ... J Troy Littleton
    Loss of the decoy SNARE Tomosyn enhances synaptic vesicle docking and neurotransmitter release and regulates release and plasticity differences between tonic and phasic motoneurons in Drosophila.
    1. Neuroscience

    Distinct dendritic Ca2+ spike forms produce opposing input-output transformations in rat CA3 pyramidal cells

    Ádám Magó, Noémi Kis ... Judit K Makara
    Dendritic patch-clamp recordings combined with two-photon imaging and glutamate uncaging reveal two types of regenerative calcium spikes in the dendrites of CA3 pyramidal neurons from rat hippocampus.
    1. Cell Biology
    2. Neuroscience

    Giant ankyrin-B mediates transduction of axon guidance and collateral branch pruning factor sema 3A

    Blake A Creighton, Simone Afriyie ... Damaris N Lorenzo
    Giant ankyrin-B enables the transduction of Sema 3A repelling cues and is important for normal axonal connectivity.