In monkeys making decisions that balance noisy evidence and reward expectation, frontal cortical and caudate activity reflect different computational components that are related to the monkeys' strategy.
Thomas Ridler, Jonathan Witton ... Jonathan T Brown
Dementia-related tau pathology reduces speed encoding in the medial entorhinal cortex and is associated with reduced grid cell function, whilst head direction tuning remains intact.
Laminar fMRI reveals that adaptive processing involves recurrent processing within visual cortex and top-down influences from posterior parietal cortex via feedback.
Aberration correction using 3D microprinting in ultrathin microendoscopes allows two-photon imaging of large neuronal networks with homogeneously high spatial resolution and minimal invasiveness in the deep mouse brain.
Shaun S Sanders, Luiselys M Hernandez ... Gareth M Thomas
ZDHHC14 controls palmitoylation and axon initial segment targeting of PSD93 and Kv1-family potassium channels, events that are essential for normal neuronal excitability.
Prenatal stress is transmitted to infant development through cortisol, which imparts sex-specific effects on the development and connectivity of the amygdalae.
Qiaochu Li, Daniel-Cosmin Marcu ... Karl Emanuel Busch
Chronic excitation of the Caenorhabditis elegans oxygen-sensing neurons alters calcium homeostasis to accelerate the decline of neural plasticity with age.
Monitoring the formation of two distinct arrangements in early amyloid-ß aggregation by mass spectrometry and ion mobility allows determination of the effect of potential drug candidates.
