Chengjie G Huang, Michael G Metzen, Maurice J Chacron
Neurophysiological and behavioral approaches reveal how coordinated input from descending pathways shapes the tuning properties of electrosensory neurons in order to optimize coding of natural stimuli through temporal whitening.
Arnaud L Lalive, Anthony D Lien ... Anatol C Kreitzer
While the basal ganglia have long been thought to mediate learning through dopamine-dependent striatal plasticity, their regulation of motor thalamus plays an unexpected and critical role in reinforcement.
Computational model reveals how the fast exchange of neurotransmitter receptors between synapses induces a competition leading to a transient form of heterosynaptic plasticity and shaping the induction of homosynaptic plasticity.
Alexandria H Jaeger, Molly Stanley ... Michael D Gordon
Unlike other taste modalities, the Drosophila taste system encodes salt taste combinatorially across multiple sensory neuron classes, which combine to produce behavioural valence and plasticity.
Dopamine neurons make novel glutamatergic connections to striatal cholinergic interneurons in the lateral dorsal striatum that are mediated by metabotropic glutamate receptors coupled to TrpC channels.
Jordan W Squair, Seth Tigchelaar ... Michael A Skinnider
Integrating decades of small-scale experiments with human gene expression data provides a systems-level view of the coordinated molecular processes triggered by spinal cord injury, and their relationship to recovery.
Oleg Tolstenkov, Petrus Van der Auwera ... Alexander Gottschalk
The 'missing' class of Caenorhabditis elegans excitatory motor neurons, AS, contribute to propagation and coordination of body waves, integrating information from, and feeding back to premotor interneurons byelectrical signaling.
Retrograde transport of NT-3 stimulated the reorganization of lumbar neural circuitry and synaptic connectivity remote to a thoracic SCI, along with improved behavioral recovery.