Browse our latest Neuroscience articles

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    1. Neuroscience

    Different contributions of preparatory activity in the basal ganglia and cerebellum for self-timing

    Jun Kunimatsu, Tomoki W Suzuki ... Masaki Tanaka
    Neuronal activity in the striatum keeps track of elapsed time during the time production task while that in the cerebellum correlates with stochastic variation of self-timing in the range of several hundreds of milliseconds.
    1. Cell Biology
    2. Neuroscience

    Matrin 3-dependent neurotoxicity is modified by nucleic acid binding and nucleocytoplasmic localization

    Ahmed M Malik, Roberto A Miguez ... Sami J Barmada
    The deposition of Matrin 3, a DNA/RNA binding protein implicated in ALS and FTD, results in neurodegeneration dependent upon its localization, self-association, and ability to bind nucleic acids.
    1. Neuroscience

    Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice

    Li Fan, Yichao Lu ... Qiang Wu
    A general cytoplasmic signaling mechanism for the novel functions of diverse alpha protocadherins in cortical neuron migration and actin cytoskeletal dynamics as well as dendrite morphogenesis in the brain.
    1. Neuroscience

    Assessing reliability in neuroimaging research through intra-class effect decomposition (ICED)

    Andreas M Brandmaier, Elisabeth Wenger ... Ulman Lindenberger
    In human neuroimaging, the intra-class effect decomposition (ICED) framework indexes overall reliability, and enables researchers to identify and quantify multi-source contributions to measurement error with the goal of developing more reliable measures.
    1. Neuroscience

    Phase-tuned neuronal firing encodes human contextual representations for navigational goals

    Andrew J Watrous, Jonathan Miller ... Joshua Jacobs
    Prospective navigational goals are represented by single neuron firing rates and firing relative to slow oscillatory phase (phase coding) in the human medial temporal lobe.
    1. Cell Biology
    2. Neuroscience

    Tenectin recruits integrin to stabilize bouton architecture and regulate vesicle release at the Drosophila neuromuscular junction

    Qi Wang, Tae Hee Han ... Mihaela Serpe
    Characterization of Tnc as a selective integrin ligand at the Drosophila NMJ allows for unprecedented insights into our understanding of extracellular matrix/integrin interactions at synaptic locations and reveals novel, distinct presynaptic and postsynaptic integrin functions.
    1. Neuroscience

    Large-scale network integration in the human brain tracks temporal fluctuations in memory encoding performance

    Ruedeerat Keerativittayayut, Ryuta Aoki ... Kiyoshi Nakahara
    Graph analysis revealed that spontaneous fluctuations of episodic-memory encoding performance associate with time-varying brain connectivity networks.
    1. Neuroscience

    Orbital frontal cortex updates state-induced value change for decision-making

    Emily T Baltz, Ege A Yalcinbas ... Christina M Gremel
    Orbital frontal cortex projection neuron activity is necessary to update state-dependent value change to control model-based behavior.
    1. Neuroscience

    Multi-scale mapping along the auditory hierarchy using high-resolution functional UltraSound in the awake ferret

    Célian Bimbard, Charlie Demene ... Yves Boubenec
    Functional UltraSound imaging allows mapping tonotopic organisation in multiple auditory subcortical and cortical brain structures with an unprecedented spatial functional resolution, while giving access to long-distance top-down connectivity pattern from frontal cortex to auditory cortex.
    1. Neuroscience

    Adaptive coding for dynamic sensory inference

    Wiktor F Młynarski, Ann M Hermundstad
    To make reliable but metabolically efficient perceptual inferences in a changing world, neural systems should dynamically adapt based on surprise and uncertainty about the sensory environment.