Computational modeling motivated by recent experiments clarifies biophysical mechanisms generating the rhythm and amplitude of breathing at the level of neurons and brain circuits in mammals.
C Joseph Burnett, Samuel C Funderburk ... Michael J Krashes
A rich behavioral data set reveals the complex interactions and influence motivational systems have on one another, driving competition and optimal expression of behavior.
Consolidation of long-term courtship memory in Drosophila is mediated by a novel class of sleep promoting neurons that reactivates dopaminergic neurons engaged earlier in memory acquisition during post-learning sleep.
The SNAP-25 linker acts as a functional component of SNARE complexes, initially facilitating SNARE interactions and later promoting fusion triggering and pore evolution by local membrane contacts.
Subtypes of dendrite-targeting somatostatin cells segregate into separate networks by specifically connecting with neurons in different layers, forming circuits that could independently control different input pathways to the neocortex.
Perception in autism is sensitive to absolute rather than to relative metrics of the environment, encoding changes in the environment without calibrating the changes relative to reference stimulation.
Rajtarun Madangopal, Brendan J Tunstall ... Bruce T Hope
Stimuli signaling reward availability potentiate and control relapse for up to 300 days of abstinence following cocaine, but not food, self-administration in rats.
