Combining GABA with fMRI measurements in the human brain uncovers distinct suppression mechanisms that optimize perceptual decisions through learning and experience-dependent plasticity in the visual cortex.
Katrin H Preller, Joshua B Burt ... Alan Anticevic
LSD induces a pattern of changed global brain connectivity characterized by hypo-connectivity in associative areas and hyper-connectivity across sensory and somatomotor areas that is dependent on the serotonin 2A receptor.
Kira M Düsterwald, Christopher B Currin ... Joseph V Raimondo
Mathematical models with experimental validation show that chloride transporters in the cell membrane, and not negatively charged impermeant molecules, generate the driving force used by GABA receptors to silence neurons.
Dopamine is able to ensure that neural networks maintain critical features of their output, such as synchrony of neuron firing, by directly increasing coupling strength to ensure robust output is maintained.
Simultaneous EEG-fMRI reveals neural representations of decision confidence unfolding prior to explicit perceptual choices, in a region of the ventromedial prefrontal cortex typically linked to reward processing and value-based decisions.
Ryan T Dosumu-Johnson, Andrea E Cocoran ... Susan M Dymecki
Pet1 neurons actively maintain cardiorespiratory tone and dynamic range in mouse neonates and critically support the recovery response to apneas, informing brain findings in the sudden infant death syndrome.
Cortical oscillations in human MEG are lamina-specific, with low-frequency activity predominating in deep, and high-frequency activity in more superficial layers of sensory and motor cortices.
Research into light-gated ion channels called channelrhodospins laid the foundations for the development of optogenetics, a technique that has gone on to revolutionize neuroscience.
Tom Alisch, James D Crall ... Benjamin L de Bivort
A new versatile, autonomous, robotic experimental platform (MAPLE) can increase the throughput of biological experiments by automating the growth and phenotyping of a variety of model organisms.
