Browse our latest Neuroscience articles

What can artificial intelligence learn from neuroscience, and vice versa?.

A multi-compartment spiking neural network model demonstrates that biologically feasible deep learning can be achieved if sensory inputs and higher-order feedback are received by different dendritic compartments.

Electrophysiological and optical analysis of neurotransmitter release at central synapses reveals that glutamate signalling is not required for the long-term potentiation (LTP) of presynaptic function, and instead only promotes presynaptic long-term depression (LTD).

Coordination between the brainstem and the cortex helps to ensure that urination occurs at an appropriate time.

Neural and network activity within a pontine-cortical micturition circuit are finely coordinated with urodynamics to assure appropriate voiding behaviors.

The silent production of words in one's mind generates an efference copy that is similar in nature to the efference copy associated with overt vocalization.

Increasing PI(4,5)P2 on a sub-second timescale using a novel, membrane-permeant UV activatable PI(4,5)P2 molecule augments exocytosis which requires the PI(4,5)P2 interacting exocytotic proteins Munc13-2 and synaptotagmin-1.

Inhibition of serotonin transporter activity, by fluoxetine treatment, in early post-natal life induces persistent apnea in wild-type mice but restores normal breathing in Necdin-KO pups that reproduce breathing abnormalities observed in Prader-Willi syndrome.

Single-neuron synaptic imaging in vivo demonstrates that highly conserved molecules such as UNC-13, UNC-18, and protein kinase C, which are found at essentially every synapse make different functional contributions in Caenorhabditis elegans glutamatergic neurons.

Genetic experiments in zebrafish identify neuropeptide VF (NPVF) signaling and NPVF-expressing neurons as a novel vertebrate hypothalamic sleep-promoting system that is functionally conserved with invertebrates.