Browse our latest Neuroscience articles

Drosophila nociceptive neurons convert high-intensity stimuli into characteristic fluctuations of firing rates, quiescent periods of which are regulated by hyperpolarization through small conductance Ca²⁺-activated K⁺ channels.

The locus coeruleus is organised into functional modules with subsets of noradrenergic neurones independently projecting to the spinal cord and prefrontal cortex to exert discrete, antithetical modulatory actions on a range of pain-related behaviours.

Neurite arbors of VGluT3-expressing amacrine cells (VG3-ACs) process visual information locally uniformly detecting object motion while varying in contrast preferences; and in spite of extensive overlap between arbors of neighboring cells population activity in the VG3-AC plexus encodes stimulus positions with subcellular precision.

Non-invasive disinhibition of the oculomotor system shows that ongoing preparatory activity in the superior colliculus has movement-generating potential and need not rise to threshold in order to produce a saccade.

Posterior parietal cortex provides an estimation of the location of an object with respect to the body and uses this information to plan appropriate gait changes to negotiate such an obstacle.

Single-nociceptor tracing reveals a novel somatotopic organization for the mammalian pain system, and physiological recordings and peripheral optogenetic behavior assays suggest that it is a possible mechanism underlying region-specific pain sensation.

The mobilization or silencing of two heterogeneous pools of synaptic vesicles via different frequencies probably enables granule cell to Purkinje cell synapses to better discriminate between the high-rate code of sensory information and background noise.

The recently characterized opsin group of xenopsins is likely a major player in animal eye evolution and may have been present in an ancient, highly plastic eye photoreceptor cell type.

Astrocytes modulate neuronal networks during hypercapnia, introducing a novel gliotransmitter pathway where prostaglandin E2 regulates breathing.

Serotonergic signaling regulates sleep homeostasis through 5HT2b receptor in a small subset of neurons in the dorsal fan-shaped body in drosophila.