Browse our latest Neuroscience articles

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    1. Neuroscience

    Neural computations underlying inverse reinforcement learning in the human brain

    Sven Collette, Wolfgang M Pauli ... John O'Doherty
    The human brain is capable of implementing inverse reinforcement learning, where an observer infers the hidden reward structure of a decision problem solely through observing another individual take actions.
    1. Neuroscience

    The large-scale organization of shape processing in the ventral and dorsal pathways

    Erez Freud, Jody C Culham ... Marlene Behrmann
    Functional neuroimaging reveals sensitivity to shape information and correlation between brain activation and perceptual behaviour in both dorsal and ventral visual pathways, thereby challenging the strict binary distinctions between the two pathways.
    1. Neuroscience

    SynEM, automated synapse detection for connectomics

    Benedikt Staffler, Manuel Berning ... Moritz Helmstaedter
    The detection of chemical synapses in 3-dimensional electron microscopy data has been automated such that synapses in large-scale connectivity maps of the cerebral cortex, connectomes, can be charted without the need for human interaction.
    1. Neuroscience

    Cortex-wide BOLD fMRI activity reflects locally-recorded slow oscillation-associated calcium waves

    Miriam Schwalm, Florian Schmid ... Albrecht Stroh
    Locally recorded calcium events related to slow wave activity show a global cortical fMRI BOLD correlate, establishing a direct relation between a basic neurophysiological signal and the macroscopic perspective of pre-clinical fMRI.
    1. Neuroscience

    Functional MRI: Making connections in the brain

    Alex TL Leong, Ed X Wu
    Simultaneous measurements of neuronal activity and fMRI signals in the rat brain have shed new light on the origins of resting-state fMRI connectivity networks.
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    1. Neuroscience

    A double-sided microscope to realize whole-ganglion imaging of membrane potential in the medicinal leech

    Yusuke Tomina, Daniel A Wagenaar
    For the first time, action potentials and subthreshold postsynaptic potentials of almost all individual identifiable neurons within a functional unit of the leech nervous system were simultaneously imaged during sensory processing and behavioral generation.
    1. Neuroscience

    Parvalbumin-positive interneurons mediate neocortical-hippocampal interactions that are necessary for memory consolidation

    Frances Xia, Blake A Richards ... Paul W Frankland
    Electrophysiological and behavioural experiments reveal that parvalbumin interneuron-mediated increases in neocortical-hippocampal interactions are necessary for successful memory consolidation.
    1. Neuroscience

    Striatal adenosine A2A receptor neurons control active-period sleep via parvalbumin neurons in external globus pallidus

    Xiang-Shan Yuan, Lu Wang ... Zhi-Li Huang
    Rostral and central striatum controls slow-wave sleep during active phase in mice.
    1. Neuroscience

    Neural and computational processes underlying dynamic changes in self-esteem

    Geert-Jan Will, Robb B Rutledge ... Raymond J Dolan
    Self-esteem, the value that people ascribe to the self, is represented in the ventromedial prefrontal cortex and dynamically updated when people learn how others value them.
    1. Neuroscience

    Theta-burst microstimulation in the human entorhinal area improves memory specificity

    Ali S Titiz, Michael R H Hill ... Itzhak Fried
    Precisely targeted, low current brain microstimulation is sufficient to enhance human memory.