Browse our latest Neuroscience articles

A new member of the family of light-sensitive proteins called opsins has stirred up our view of photoreceptors.

Multi-modal imaging, genetic and behavioral findings in humans and mice revealed that metabotropic glutamate receptors of subtype 5 contribute to the molecular machinery keeping track of sleep need and coping with physiological and behavioral consequences of sleep loss, pointing to novel targets for improved wakefulness and sleep.

The integration of a novel high spatiotemporal resolution volume imaging technique and a fast 3D tracking system allows capturing whole brain neural activities in a freely behaving larval zebrafish.

Establishment of two-photon imaging with a 1100-nm laser, which underfills the objective's back aperture, detects activity of multiple neurons in the prelimbic area and hippocampal CA1 region of the intact mouse brain.

Pedunculopontine neurons can evoke burst spiking in substantia nigra dopaminergic neurons without engaging a subtype of glutamate receptor previously thought to be necessary for this spiking mode.

Non-invasive brain stimulation tests and refines a model of lateral prefrontal cortex neural dynamics supporting cognitive control.

Climbing fiber glutamate spillover enhances response complexity and regulates signaling to Golgi cells through a form of transmission not constrained to synapses.

Unbiased functional proteomics reveal that protein interactions are a key regulator of the strength of synaptic inhibition in neurons of the central nervous system.

Synaptic scaling maintains motor output from the respiratory network of bullfrogs after months of inactivity in the winter, providing evidence for homeostatic plasticity in response to large ecologically relevant perturbations in neuronal activity.

Synaptic zinc is a novel modulator of cortical sound processing - a modulator that increases the gain of principal neurons, but reduces the gain of interneurons.