Chia-Wei Chang, Julia R Wilkerson ... Kimberly M Huber
Increasing periods of neuronal activity progressively weaken and then eliminate synapses through the activation of specific transcription factors and genes.
Salvatore Lecca, Frank Julius Meye ... Manuel Mameli
Glutamatergic signaling from the lateral hypothalamus instructs lateral habenular neurons for encoding aversive external stimuli to subsequently guide escape behaviours.
A fundamental lower-bound on memory recall precision, which declines with storage duration and number of stored items, is derived, and human performance is shown to be well-fit by this theoretical bound.
Combination of in vitro and in vivo approaches reveal how learning suppresses the microRNA system to trigger de novo synthesis of plasticity proteins, a missing link in the current model of microRNA-mediated translation in persistent synaptic plasticity and memory.
Madeline G Andrews, Lorenzo M del Castillo ... Samantha J Butler
Members of the BMP family of growth factors act as a reiterative code of distinct activities to direct the identities of different classes of sensory neurons in the spinal cord.
Synaptic defects previously attributed to loss of kinesin function are found to be mediated by the Wnd/DLK axonal injury signaling pathway, which restrains the total levels of presynaptic proteins in response to their accumulation.
Amber M Fyall, Yasmine El-Shamayleh ... Anitha Pasupathy
Complementary neural codes in frontal and visual cortex support a role for feedback signals in the representation and recognition of partially occluded objects.
Magnetothermal neuromodulation providing quick, tetherless, precise on and off switching of neurons deep in the brain of freely moving animals is orthogonal to optogenetics and a breakthrough in remote modulation techniques.
