Browse our latest Neuroscience articles

Page 569 of 616
    1. Cell Biology
    2. Neuroscience

    Dendritic mitochondria reach stable positions during circuit development

    Michelle C Faits, Chunmeng Zhang ... Daniel Kerschensteiner
    Mitochondria reach stable positions in dendrites during a critical developmental period of high motility.
    1. Neuroscience

    A serial multiplex immunogold labeling method for identifying peptidergic neurons in connectomes

    Réza Shahidi, Elizabeth A Williams ... Gáspár Jékely
    A new technique called ‘siGOLD’ allows neural circuits to be mapped using a combination of antibody labeling and electron microscopy.
    1. Neuroscience

    Neural evidence accumulation persists after choice to inform metacognitive judgments

    Peter R Murphy, Ian H Robertson ... Redmond G O'Connell
    Error detection is contingent on the continuation of evidence accumulation after choice commitment, and the speed and accuracy of this process are modulated by high-level signals from medial frontal cortex.
    1. Neuroscience

    Hippocampal ensemble dynamics timestamp events in long-term memory

    Alon Rubin, Nitzan Geva ... Yaniv Ziv
    Temporally close events share a common timestamp regardless of the spatial context in which they occur.
    1. Neuroscience

    Synchronized amplification of local information transmission by peripheral retinal input

    Pablo D Jadzinsky, Stephen A Baccus
    Peripheral retinal input transiently amplifies information transmission from ganglion cells, dynamically allocating the resources of neural activity to times of expected high information content.
    1. Neuroscience

    Mouse models of human PIK3CA-related brain overgrowth have acutely treatable epilepsy

    Achira Roy, Jonathan Skibo ... Kathleen J Millen
    Acute one-hour treatment of Pik3ca mutant mice with a novel anti-epilepsy drug suppresses seizures despite continued developmental brain dysmorphology, promising a new therapeutic strategy for patients with intractable pediatric epilepsy.
    1. Developmental Biology
    2. Neuroscience

    Area-specific development of distinct projection neuron subclasses is regulated by postnatal epigenetic modifications

    Kawssar Harb, Elia Magrinelli ... Christian Alfano
    Lmo4 specifies two neuron subclasses in the mouse neocortex by promoting postnatal co-expression of the transcription factors Ctip2 and Satb2 via chromatin remodelling in a time and area-specific manner.
    1. Neuroscience

    Specialized areas for value updating and goal selection in the primate orbitofrontal cortex

    Elisabeth A Murray, Emily J Moylan ... Janita Turchi
    Within the monkey orbitofrontal cortex, a posterior part learns new values, whereas an anterior part translates this knowledge into advantageous decisions.
    1. Developmental Biology
    2. Neuroscience

    Genetic mechanisms control the linear scaling between related cortical primary and higher order sensory areas

    Andreas Zembrzycki, Adam M Stocker ... Dennis DM O'Leary
    Primary and higher order visual area dimensions in the neocortex are determined by the same genetic mechanisms during development which in turn also control the proportionate scaling between them.
    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    Photo-switchable tweezers illuminate pore-opening motions of an ATP-gated P2X ion channel

    Chloé Habermacher, Adeline Martz ... Thomas Grutter
    The gating mechanism of trimeric ATP-gated P2X receptors has been explored using photo-switchable cross-linkers, via a versatile strategy that could be applied to other membrane proteins.