Parthiv Haldipur, Gwendolyn S Gillies ... Kathleen J Millen
The mesenchyme surrounding the developing brain plays a significant role in controlling the fundamental growth and patterning of the cerebellum, and misregulation of this signalling can lead to important neurodevelopmental disorders.
The sleep cycle of nematode worms adjusts to compensate for sleep disturbances, with neuropeptide Y involved in the response to minor disruptions, and the transcription factor DAF-16/FOXO in the response to major disruptions.
Output neurons in the mushroom body of the fruit fly brain encode the positive or negative survival value of stimuli, enabling insects to choose adaptive approach and avoidance behaviors through associative learning.
A map of the entire array of cell types and potential projections in the mushroom body of the fruit fly brain provides insights into the circuitry that supports learning of stimulus-reward and stimulus–punishment associations.
Ann M Hermundstad, John J Briguglio ... Gašper Tkačik
Psychophysical measures of human sensitivity to visual patterns reveal that the brain preferentially processes those features of stimuli that are more variable in the natural world.
Lrp4 mutant mice display profound deficits in cognitive tasks that assess learning and memory with disruptions in the subcellular organization of synaptic inputs and synaptic plasticity in the hippocampus.
Spontaneous fusion of vesicles at synapses is regulated independently of fusion triggered by action potentials, adding to evidence that the two types of fusion have distinct functions.
