Xueying Wang, John A Hayes ... Christopher A Del Negro
Laser-ablating neurons of a single genetic class reveals that Dbx1-derived interneurons comprise core respiratory rhythmogenic and premotor circuits and provides quantitative cellular parameters that govern network functionality
Shawn McClelland, Gary P Brennan ... Tallie Z Baram
Uncovering the mechanisms by which the transcription factor NRSF contributes to the development of epilepsy reveals that the regulation of gene expression by transcription factors in the brain is more finely-tuned than previously thought.
Diasynou Fioravante, YunXiang Chu ... Wade G Regehr
Genetic and electrophysiology experiments provide the first direct evidence that protein kinase C is a calcium-sensing protein in post-tetanic potentiation, a form of synaptic plasticity that supports short-term memory.
Conditional knockout of the small GTPase Cdc42 in excitatory neurons of the mouse forebrain leads to impaired long-term synaptic plasticity and impaired retrieval of remote memory.
Maciej M Jankowski, Md Nurul Islam ... Shane M O'Mara
Neurons that provide information about the direction of the head are present in nucleus reuniens and can potentially directly influence spatial processing in the hippocampus.
A distinct cortical region serves head gaze following, and is needed to establish joint attention with others and to ultimately develop a theory of others' mind.
Analysis of neurons that lack the two neuronal dynamins, dynamin 1 and 3, demonstrates a pathway of synaptic vesicle reformation that does not require these two dynamins or clathrin-dependent budding.
Identification of two classes of mouse vomeronasal receptors for female pheromone cues suggests distinct gating mechanisms in pheromone-triggered reproductive behaviors.