A comparative study of Purkinje dendrite morphology, input arrangement, and regional subtype distribution shows human cells evade constraint by cortical thickness to be both quantitatively and qualitatively distinct from mouse.
Lauren J Kreeger, Suraj Honnuraiah ... Lisa Goodrich
In the mammalian auditory brainstem, inhibitory inputs onto octopus cell dendrites enhance coincidence detection computations and support precise yet flexible temporal processing for rapid sound onsets and frequency modulations.
Phillip P Witkowski, Lindsay JH Rondot ... Erie Boorman
Orbitofrontal cortex and hippocampus reinstate representations of causal choices to associate with delayed outcomes, and the frontal pole supports this credit assignment process by maintaining pending choices during interim decisions.
Carlos A Sánchez-León, Guillermo Sánchez-Garrido Campos ... Javier Márquez-Ruiz
The neuromodulatory effects of cerebellar tDCS depend on Purkinje cell somatodendritic orientation relative to the electric field, revealing a key factor for optimizing stimulation protocols and computational models.
Novel tools that allow neuron-specific investigations of the structure controlling sleep regulation in fruit flies reveal the extent of neuronal heterogeneity.
Hippocampal sharp wave-ripples during sleep are enhanced by food intake in a calorie-dependent manner and are associated with increased activity of lateral hypothalamic GABAergic neurons.
Aleksandra Prochera, Anoohya N Muppirala ... Meenakshi Rao
Genetic depletion of enteric glia in vivo disrupts antimicrobial peptide secretion by Paneth cells to change fecal microbial composition but does not broadly alter other intestinal programs.
