Browse our latest Neuroscience articles

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    1. Neuroscience

    Subcortical correlates of consciousness with human single neuron recordings

    Michael Pereira, Nathan Faivre ... Olaf Blanke
    Subcortical brain structures contain neurons encoding subjective reports of stimulus detection in human participants, suggesting a role for conscious perception.
    1. Cell Biology
    2. Neuroscience

    Glutamine catabolism supports amino acid biosynthesis and suppresses the integrated stress response to promote photoreceptor survival

    Moloy T Goswami, Eric Weh ... Thomas J Wubben
    For the first time, mouse models reveal the metabolic dependency of photoreceptors on glutamine catabolism in vivo and further demonstrate the flexibility of photoreceptors to utilize fuel sources beyond glucose.
    1. Cell Biology
    2. Neuroscience

    Vision: A pathway to sight

    Katherine J Wert
    The breakdown of glutamine is an important metabolic pathway for the health and survival of rod photoreceptors within the retina.
    Version of Record
    Insight
    1. Neuroscience

    Spatial periodicity in grid cell firing is explained by a neural sequence code of 2-D trajectories

    Rebecca RG, Giorgio A Ascoli ... Holger Dannenberg
    The characteristic hexagonal firing pattern of grid cells emerges as the most parsimonious solution to a trajectory code by cell sequences.
    1. Neuroscience

    Growth in early infancy drives optimal brain functional connectivity which predicts cognitive flexibility in later childhood

    Chiara Bulgarelli, Anna Blasi ... the BRIGHT Study Team
    Revised
    Reviewed Preprint v2
    Updated
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    • Solid
    1. Neuroscience

    Flower/FLWR-1 regulates neuronal activity via the plasma membrane Ca2+ ATPase to promote recycling of synaptic vesicles

    Marius Seidenthal, Jasmina Redzovic ... Alexander Gottschalk
    Caenorhabditis elegans FLWR-1/Flower is required for efficient synaptic vesicle recycling and does so through a functional and possibly direct physical interaction with the plasma membrane Ca2+ ATPase, MCA-3.
    1. Medicine
    2. Neuroscience

    mTOR inhibition in Q175 Huntington’s disease model mice facilitates neuronal autophagy and mutant huntingtin clearance

    Philip Stavrides, Chris N Goulbourne ... Dun-Sheng Yang
    ALP alterations in Q175 brains are late-onset, mild, existing at the later phases of the pathway, and stimulating autophagy at early disease progression enhances mHTT clearance to ameliorate HD pathology.
    1. Neuroscience

    Sensitivity to visual features in inattentional blindness

    Makaela Nartker, Chaz Firestone ... Ian Phillips
    As a group, inattentionally blind participants can successfully report the location, color, and shape of stimuli they deny noticing, and exhibit a systematic bias to report not noticing.
    1. Neuroscience

    Viral-mediated Pou5f1 (Oct4) overexpression and inhibition of Notch signaling synergistically induce neurogenic competence in mammalian Müller glia

    Nguyet Le, Sherine Awad ... Seth Blackshaw
    Viral-mediated Oct4 overexpression induces direct conversion of wildtype mammalian Müller glia to bipolar neurons, and this process is synergistically enhanced by loss of Notch signaling.