A biologically plausible reinforcement learning model that integrates associative memory and hippocampal remapping explains context-dependent flexible behavior, neural dynamics, and psychosis-related symptoms.
Marco Nigro, Lucas Silva Tortorelli ... Hongdian Yang
Inhibiting locus coeruleus input to the medial prefrontal cortex in mice impaired task performance, affected the tuning of single cortical neurons and disrupted population dynamics and encoding capacity during attentional switching.
Mofida Abdelmageed, Premkumar Palanisamy ... Anirban Paul
Progressive DNA polymerase kappa relocalization in aging neurons associates with increased DNA damage and identifies a novel cell type- and activity-dependent role in neuronal genome maintenance.
Dissociable neural signatures of integration and segregation provide the first direct neuroimaging evidence for the integration-segregation theory of exogenous attention.
Mary L Phillips, Nicolai T Urban ... Ryohei Yasuda
Multiplexed spectral fingerprinting through a single implanted GRIN lens enables projection-resolved functional imaging of up to nine neuronal populations in freely behaving animals without post hoc histology.
Ryan T Maloney, Athena Q Ye ... Benjamin L de Bivort
Individual flies have idiosyncratic preferences that shift over their lifetime in a way that depends on genotype and may be adaptive to rapidly changing environmental pressures.
