Monique Marylin Alves de Almeida, Yves De Repentigny ... Rashmi Kothary
A liver-specific depletion of the survival motor neuron protein in a mouse model unveils a compelling and intricate connection between liver function and pancreatic abnormalities in spinal muscular atrophy.
Electrochemical recordings of cortico-striatal glutamatergic signaling, and chemogenetic inhibition of such signaling, revealed an essential role of cortico-striatal input for cued action selection, but not for cued stopping.
The Apollo implant, an open-source device tested in eight laboratories, can be used to reversibly implant Neuropixels probes and track the activity of populations of neurons across days.
Seemingly disparate property-based tasks (oddball search, same-different and symmetry) are solved by computing a novel image property, visual homogeneity, which is localized to the object selective cortex.
Ana Fló, Lucas Benjamin ... Ghislaine Dehaene-Lambertz
Human neonates process regularities in speech's phonetic and voice content in parallel, but only phonetic regularities evoke a specific ERP component in a post-learning phase.
Predictive pharmacology based on behavioural fingerprinting can identify druggable pathways that are altered or renormalized in zebrafish larvae that harbor mutations in early and late-onset Alzheimer's disease risk genes.
Kaspar E Vogt, Ashwinikumar Kulkarni ... Robert W Greene
Sleep's role to down-scale glutamate, excitatory, frontal cortical synapses is extended to include an up-scaling of metaplastic LTP potential, in recovery from prolonged waking induced saturation of this LTP potential.
