Allison T Goldstein, Terrence R Stanford, Emilio Salinas
Psychophysical measurements using time pressure indicate that when attention is willfully deployed, a congruent scaccade is automatically planned, but the coupling is weak and can be rapidly broken.
New methods for investigating connectivity between genetically defined neuronal populations are introduced and used to investigate the organisation of excitatory-inhibitory interactions in the superficial entorhinal cortex.
Giordano de Guglielmo, Lieselot Carrette ... Olivier George
Genetically diverse rats reveal a single underlying construct linking key addiction-like behaviors, challenging compulsivity as an independent measure, and offering a new perspective on vulnerability and resilience to addiction.
The established triple co-culture blood-–brain barrier (BBB) model could be used for predicting drugs’ BBB permeability, and co-culture with neurons and astrocytes enhanced brain endothelial cells’ integrity by secreting GDNF, which upregulated claudin-5 and VE-cadherin expression.
The representation of odor transforms from high dimensional, population level encoding of valence and identity in the OT, to a low dimensional representation of valence in the VP.
Coupling between subcellular localization and protein turnover of a neuronal stress kinase, DLK, and its role in neuronal stress responses in Drosophila.
Typhaine Comyn, Thomas Preat ... Pierre-Yves Plaçais
In neurons of the Drosophila brain’s memory center, PKCδ relays a post-learning dopamine signal to mitochondria, boosting their metabolic activity and thereby unlocking long-term memory formation.
Sachin P Gadani, Saumitra Singh ... Pavan Bhargava
Leptomeningeal inflammation in a mouse model of multiple sclerosis triggers deeply penetrating gene changes in underlying brain tissue, described using spatial transcriptomics.
