Neuroscience

Neuroscience

eLife publishes research including brain function, neuronal circuits, synapses, sensory processing and motor pattern generation. Learn more about what we publish and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Neuroscience

    A MAC2-positive progenitor-like microglial population is resistant to CSF1R inhibition in adult mouse brain

    Lihong Zhan et al.
    A hidden population of microglial progenitors with distinct transcriptomic signatures are among homeostatic microglia in adult mouse brain.
    1. Developmental Biology
    2. Neuroscience

    Adrenergic activation modulates the signal from the Reissner fiber to cerebrospinal fluid-contacting neurons during development

    Yasmine Cantaut-Belarif et al.
    The Reissner fiber in the cerebrospinal fluid is required for a signal integrated by developing sensory neurons and modulated by catecholamines to control the embryo posterior axis morphogenesis.
    1. Neuroscience

    Improving emotional-action control by targeting long-range phase-amplitude neuronal coupling

    Bob Bramson et al.
    Non-invasive manipulation of endogenously coupled neural rhythms enhances human control of social-emotional actions.
    1. Neuroscience

    SARM1 depletion rescues NMNAT1-dependent photoreceptor cell death and retinal degeneration

    Yo Sasaki et al.
    A mouse model of retinal degeneration reveals a common mechanism for axonal degeneration and photoreceptor cell death and identifies SARM1 as a therapeutic candidate for retinopathies.
    1. Neuroscience

    Distinct hierarchical alterations of intrinsic neural timescales account for different manifestations of psychosis

    Kenneth Wengler et al.
    fMRI evidence for distinct hierarchical alterations in intrinsic neural timescales for different positive symptoms of schizophrenia support hierarchical perceptual-inference models of psychosis and suggest local increases in excitation-inhibition ratio.
    1. Neuroscience

    VIP interneurons in mouse primary visual cortex selectively enhance responses to weak but specific stimuli

    Daniel J Millman et al.
    Measurements of visual response to motion of different contrasts along with network modeling reveals a microcircuit in superficial layers of cortex that regulates the gain regime.
    1. Medicine
    2. Neuroscience

    APOE2 is associated with longevity independent of Alzheimer’s disease

    Mitsuru Shinohara et al.
    Translational evidence indicates APOE2 benefits longevity independent of its protective effects on Alzheimer’s disease, which preserved activity and the metabolism of apoE protein and associated-lipids would be key to understanding.
    1. Neuroscience

    Divergent projections of the prelimbic cortex bidirectionally regulate active avoidance

    Maria M Diehl et al.
    Projections from the prelimbic prefrontal cortex targeting the ventral striatum or the basolateral amygdala bidirectionally regulate platform-mediated active avoidance in rats.

Highlights

    1. Neuroscience

    Decoding the infrastructure of the cerebellum

    Willem S van Hoogstraten, Chris I De Zeeuw
    1. Evolutionary Biology
    2. Neuroscience

    On the origin of fly species

    Hui Gong, Lucia Prieto-Godino

Senior editors

  1. Michael Taffe
    University of California, San Diego, United States
  2. Kate Wassum
    University of California, Los Angeles, United States
  3. Huda Zoghbi
    Huda Zoghbi
    Baylor College of Medicine and Texas Children's Hospital, United States, United States
  4. See more editors