Browse our latest Physics of Living Systems articles

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    1. Computational and Systems Biology
    2. Physics of Living Systems

    Out-of-balance Growth Enables Cost-free Synthesis of the Flagellum and Other Proteins in a Single Bacterium

    Mayra Garcia-Alcala, Josiah C Kratz, Philippe Cluzel
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Developmental Biology
    2. Physics of Living Systems

    A soft active matter models explains spiral epithelial cell migration on in-vivo corneas

    Kaja Kostanjevec, Rastko Sknepnek ... Silke Henkes
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Cell Biology
    2. Physics of Living Systems

    The titin N2A-MARP signalosome constrains muscle longitudinal hypertrophy in response to stretch

    Robbert van der Pijl, Jochen Gohlke ... Coen Ottenheijm
    Titin-associated muscle ankyrin repeat proteins limit stretch-induced longitudinal muscle hypertrophy and link titin mechanosensing to mTOR signaling.
    1. Chromosomes and Gene Expression
    2. Physics of Living Systems

    Preferential formation of NUP98-KDM5A condensates at specific H3K4me3-rich loci drives leukemogenic gene expression

    Augusto Berrocal, Jonathan E Sandoval ... Bo Huang
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Chromosomes and Gene Expression
    2. Physics of Living Systems

    Cluster size determines internal structure of transcription factories in human cells

    Massimiliano Semeraro, Giuseppe Negro ... Davide Marenduzzo
    In a polymer model of chromatin that explicitly incorporates different types of transcription factors, both specialised and mixed factories emerge naturally, with their composition governed by their size.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Stabilizing by steering: Enhancing bacterial motility by non-uniform diffusiophoresis

    Viet Sang Doan, Ali Nikkhah, Sangwoo Shin
    Not revised
    Reviewed Preprint v1
    • Incomplete
    1. Physics of Living Systems

    Mechanical interaction enables a collective mode of protocell proliferation

    Yisen Li, Yilin Wu
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete
    1. Physics of Living Systems

    Design of a minimal, allosteric, and ATPase-like machine using mechanical linkages

    Tosan Omabegho
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Cooperative antibiotic response in coupled biofilm and planktonic E. faecalis communities

    Gabriela Fernandes Martins, Keanu Alexander Guardiola-Flores ... Kevin Wood
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Computational and Systems Biology
    2. Physics of Living Systems

    A coma pattern-based autofocusing method resolves bacterial cold shock response at single-cell level

    Sihong Li, Zhixin Ma ... Shuqiang Huang
    A robust autofocusing method enables continuous single-cell imaging during rapid cooling, revealing sustained bacterial proliferation hidden by growth arrest inferred from optical-density measurements.