Browse our latest Physics of Living Systems articles

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    1. Cell Biology
    2. Physics of Living Systems

    Caveolin-1 protects endothelial cells from extensive expansion of transcellular tunnel by stiffening the plasma membrane

    Camille Morel, Eline Lemerle ... Emmanuel Lemichez
    Caveolin-1 controls the width of transendothelial cell tunnels via a direct or indirect effect on membrane bending rigidity.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Potassium-mediated bacterial chemotactic response

    Chi Zhang, Rongjing Zhang, Junhua Yuan
    1. Physics of Living Systems

    Structural basis for the preservation of a subset of topologically associating domains in interphase chromosomes upon cohesin depletion

    Davin Jeong, Guang Shi ... D Thirumalai
    The finding that deletion of the genome folding motor leaves a significant fraction of a key structural feature of chromosome at the single cell and ensemble level has been explained.
    1. Neuroscience
    2. Physics of Living Systems

    C9orf72 polyPR directly binds to various nuclear transport components

    Hamidreza Jafarinia, Erik van der Giessen, Patrick R Onck
    Length-dependent interference of arginine-containing dipeptide repeat proteins with multiple components of the nucleocytoplasmic transport machinery is a potential mechanistic pathway of C9orf72 amyotrophic lateral sclerosis or frontotemporal dementia toxicity.
    1. Neuroscience
    2. Physics of Living Systems

    Neural criticality from effective latent variables

    Mia C Morrell, Ilya Nemenman, Audrey Sederberg
    Signatures of criticality that have been observed across diverse neural systems, such as power-law avalanche distributions and exponent relationships, can arise without fine-tuning in networks coupled to latent, dynamical variables.
    1. Physics of Living Systems

    A unified approach to dissecting biphasic responses in cell signaling

    Vaidhiswaran Ramesh, J Krishnan
    In-built competing effects are present at different levels in signaling networks, starting from basic biochemical building blocks to the network level, and mathematical and computational analysis reveals when they give rise to biphasic responses and what the consequences are.
    1. Physics of Living Systems

    Emergence of ion-channel mediated electrical oscillations in Escherichia coli biofilms

    Emmanuel U. Akabuogu, Victor Martorelli ... Thomas A. Waigh
    1. Cell Biology
    2. Physics of Living Systems

    The positioning mechanics of microtubule asters in Drosophila embryo explants

    Jorge de-Carvalho, Sham Tlili ... Ivo A Telley
    Using cytosolic explants from Drosophila syncytial embryos combined with quantitative microscopy and perturbations, the mechanical forces separating Drosophila microtubule asters are revealed.
    1. Physics of Living Systems

    Optical mapping of ground reaction force dynamics in freely behaving Drosophila melanogaster larvae

    Jonathan H. Booth, Andrew T. Meek ... Malte C. Gather