Browse our latest Physics of Living Systems articles

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    1. Physics of Living Systems

    How to assemble a scale-invariant gradient

    Arnab Datta et al.
    Intracellular protein gradients, which are formed by the combined action of cytoplasmic diffusion and cortical transport toward the cell pole, are solely determined by cell shape.
    1. Physics of Living Systems

    Large-scale orientational order in bacterial colonies during inward growth

    Mustafa Basaran et al.
    When crowded bacterial colonies invade a closed area, flow-induced alignment creates strong radial orientation and leads to the formation of aster defects.
    1. Cell Biology
    2. Physics of Living Systems

    Persistent cell migration emerges from a coupling between protrusion dynamics and polarized trafficking

    Kotryna Vaidžiulytė et al.
    Quantitative proof that persistent cell migration in the timescale of hours relies on a feedback between polarized trafficking and protrusive activity stabilizing cell front.
    1. Ecology
    2. Physics of Living Systems

    Particle foraging strategies promote microbial diversity in marine environments

    Ali Ebrahimi et al.
    An ecological trade-off between growth and death enables microbes with different dispersal strategies to coexist on particulate matter in the oceans.
    1. Cell Biology
    2. Physics of Living Systems

    Cortical waves mediate the cellular response to electric fields

    Qixin Yang et al.
    Electrical and biomechanical stimuli directly bias cortical signal transduction and cytoskeletal waves, and the direct bias induced by an electric field develops slowly compared to the rapid surface-receptor-mediated response to chemotactic gradients.
    1. Biochemistry and Chemical Biology
    2. Physics of Living Systems

    A coarse-grained NADH redox model enables inference of subcellular metabolic fluxes from fluorescence lifetime imaging

    Xingbo Yang et al.
    Mitochondrial metabolic fluxes display a subcellular spatial gradient within a single mouse oocyte, and the fluxes are not controlled by nutrient supply or energy demand of the cell, but by the intrinsic rates of mitochondrial respiration.
    1. Physics of Living Systems

    Humans optimally anticipate and compensate for an uneven step during walking

    Osman Darici, Arthur D Kuo
    Humans can predict and optimally plan goal-directed dynamic walking tasks that have transient events such as negotiating a sidewalk curb.
    1. Physics of Living Systems

    Epithelial-to-mesenchymal transition proceeds through directional destabilization of multidimensional attractor

    Weikang Wang et al.
    Integrated live cell imaging and image analyses in the framework of transition path theories identify epithelial-to-mesenchymal transition proceeds through parallel paths.
    1. Evolutionary Biology
    2. Physics of Living Systems

    In vivo intraoral waterflow quantification reveals hidden mechanisms of suction feeding in fish

    Pauline Provini et al.
    The integration of biplanar X-ray videos with 3D X-ray particle tracking revealed that fish use a combination of intraoral 'central jet' waterflow pattern and inertia to guide food toward the digestive tract during suction feeding.
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Chemotactic smoothing of collective migration

    Tapomoy Bhattacharjee et al.
    Studies of bacterial chemotaxis reveal how limitations in single-cell sensing of stimuli influence large-scale population morphology.