Browse our latest Physics of Living Systems articles

Page 6 of 57
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Balancing reaction-diffusion network for cell polarization pattern with stability and asymmetry

    Yixuan Chen, Guoye Guan ... Chao Tang
    Reaction-diffusion network modeling unveils general design principles that both stabilize cell polarization patterns and enable tunable interface localization, reconciling extensive experimental observations and deepening the understanding of asymmetric cell division.
    1. Physics of Living Systems

    Quantifying Intracellular Mechanosensitive Response upon Spatially Defined Mechano-Chemical Triggering

    Elaheh Zare-Eelanjegh, Renard TM Lewis ... Tomaso Zambelli
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Physics of Living Systems

    Q-learning with temporal memory to navigate turbulence

    Marco Rando, Martin James ... Agnese Seminara
    Animals may learn to locate preys effectively by memorizing short excerpts of their scent trace, which duration is dictated by the sparse nature of turbulent odor plumes.
    1. Cell Biology
    2. Physics of Living Systems

    Convergent Cellular Adaptation to Freeze-Thaw Stress via a Quiescence-like State in Yeast

    Charuhansini Tvishamayi, Farhan Ali ... Shashi Thutupalli
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Physics of Living Systems

    Physical constraints and biological regulations underlie universal osmoresponses

    Yiyang Ye, Qirun Wang, Jie Lin
    Theoretical modeling uncovers an unusual acceleration in microbial growth following osmotic shock, driven by the coordinated regulation of osmolyte production and cell-wall synthesis.
    1. Computational and Systems Biology
    2. Physics of Living Systems

    A mathematical model for ketosis-prone diabetes suggests the existence of multiple pancreatic β-cell inactivation mechanisms

    Sean A Ridout, Priyathama Vellanki, Ilya Nemenman
    A simple mathematical model, incorporating reversible deactivation of β-cells, can potentially explain the rapid onset and remission of a diabetes subtype, ketosis-prone diabetes.
    1. Physics of Living Systems
    2. Structural Biology and Molecular Biophysics

    Polyphosphate discriminates protein conformational ensembles more efficiently than DNA promoting diverse assembly and maturation behaviors

    Saloni Goyal, Divya Rajendran ... Athi N Naganathan
    Polyphosphate, a universal stress response regulator, binds distinctively to different starting ensembles of the same protein leading to either condensates or aggregates that in turn can solubilize or further aggregate, showcasing their ability to finely control the assembly process.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Heterogeneous efflux pump expression underpins phenotypic resistance to antimicrobial peptides

    Ka Kiu Lee, Urszula Łapińska ... Stefano Pagliara
    Sub-populations of non growing bacteria survive treatment with antimicrobial peptides by mounting an efflux response.
    1. Neuroscience
    2. Physics of Living Systems

    Responses to membrane potential-modulating ionic solutions measured by magnetic resonance imaging of cultured cells and in vivo rat cortex

    Kyeongseon Min, Sungkwon Chung ... Jang-Yeon Park
    Magnetic resonance imaging, through its sensitivity to ionic environments that modulate membrane potential, enables noninvasive assessment of biological systems.
    1. Physics of Living Systems

    Role of intercellular adhesion in modulating tissue fluidity

    Soumyadipta Ray, Santidan Biswas, Dipjyoti Das
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid