Browse our latest research

Page 146 of 1,897
    1. Computational and Systems Biology
    2. Neuroscience

    Deep neural networks to register and annotate cells in moving and deforming nervous systems

    Adam A Atanas, Alicia Kun-Yang Lu ... Steven W Flavell
    New machine vision tools are used to align densely packed cells recorded from live, deforming tissues and automatically annotate the identities of the recorded cell types.
    1. Neuroscience

    A three-dimensional immunofluorescence atlas of the brain of the hackled-orb weaver spider, Uloborus diversus

    Gregory Artiushin, Abel Corver, Andrew Gordus
    A detailed annotation of anatomical brain structures (some novel) of the spider Uloborus diversus is provided based on a three-dimensional immunostain atlas.
    1. Neuroscience

    Spatially periodic computation in the entorhinal-hippocampal circuit during navigation

    Bo Zhang, Xin Guan ... Jia Liu
    A threefold hippocampal code across conceptual directions, phase-locked to entorhinal grid activity, reveals a periodic mechanism through which entorhinal grids structure hippocampal vector representations.
    1. Microbiology and Infectious Disease

    Neutralizing human monoclonal antibodies that target the PcrV component of the type III secretion system of Pseudomonas aeruginosa act through distinct mechanisms

    Jean-Mathieu Desveaux, Eric Faudry ... Pascal Poignard
    Human antibodies isolated from cystic fibrosis patients against PscF and PcrV of the Pseudomonas aeruginosa Type 3 Secretion System reveal that anti-PcrV antibodies inhibit secretion through distinct mechanisms.
    1. Computational and Systems Biology
    2. Neuroscience

    Linking spinal circuit reorganization to recovery after thoracic spinal cord injury

    Natalia A Shevtsova, Andrew B Lockhart ... Simon M Danner
    A computational model mechanistically links spinal circuit reorganization to recovered locomotion after incomplete spinal cord injury.
    1. Cell Biology

    EOLA1, a novel mitochondria-localized protein critical for heart functions via regulating mitochondrial translation

    Xiaoyan Shi, Yangyi Zhang ... Hao Chen
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience

    Single molecule counting detects low-copy glycine receptors in hippocampal and striatal synapses

    Serena Camuso, Yana Vella ... Christian G Specht
    Synapses in the forebrain were thought of as purely GABAergic, yet they contain minute numbers of glycine receptors, often in the single digits.
    1. Genetics and Genomics

    SETDB1 enables development beyond cleavage stages by extinguishing the MERVL-driven two-cell totipotency transcriptional program in the mouse embryo

    Tie-Bo Zeng, Zhen Fu ... Piroska E Szabó
    Conditional genetics and single-embryo RNA-seq show that SETDB1 extinguishes the transient, retroelement-driven transcriptional programs of the totipotent two-cell state to facilitate the exit from totipotency and ensure preimplantation development.
    1. Neuroscience

    Frictional instabilities as an alternative to friction coefficient in fine touch perception

    Maryanne Derkaloustian, Pushpita Bhattacharyya ... Charles B Dhong
    To study fine touch, selecting samples based on how many mechanical instabilities they can form is more predictive than using the friction coefficient, which has been the default choice.
    1. Medicine

    The inactivation of DHHC7 in mouse liver promotes diet-induced obesity through a hepatic Prg4–GPR146 axis

    Yingmin Sun, Ying Liu ... Bing Chen
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete