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Multi-omics analyses reveal redundant functions of yeast mRNA decapping activators Scd6 and Edc3 in facilitating recruitment of helicase Dhh1 and accelerating degradation of transcripts required for respiration in glucose-replete cells.

A deep generative approach learns the translation from neurons’ electrophysiological recordings to the biophysical parameters of neuron models, assisting in the development of a detailed nervous system model.

Integrative analyses uncover RBMX2 as a pivotal mediator that bridges Mycobacterium bovis infection to epithelial–mesenchymal transition and tumor progression in the lung.

Bayesian hierarchical models offer powerful statistical tools for neuroscientists to analyze whole-brain cell count data, as demonstrated here using two example datasets from different laboratories.

PTBP1 loss in mature astrocytes causes unique astrocytic splicing changes, not neuronal-like, contrasting its role in other non-neuronal cells and indicating PTBP1 depletion alone is ineffective to drive adult-astrocyte-to-neuron conversion.