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    1. Neuroscience

    Low-dimensional olfactory signatures of fruit ripening and fermentation

    Yuansheng Zhou, Thomas F O’Connell ... Tatyana O Sharpee
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    IFIT1 is rapidly evolving and exhibits disparate antiviral activities across 11 mammalian orders

    Matthew B McDougal, Anthony M De Maria ... John W Schoggins
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Immunology and Inflammation

    PD-1 negatively regulates helper T cell differentiation into Th2

    Masaki Tajima, Naoko Ikuta ... Akio Ohta
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Compelling
    • Incomplete
    1. Microbiology and Infectious Disease

    A modified BPaL regimen for tuberculosis treatment replaces linezolid with inhaled spectinamides

    Malik Zohaib Ali, Taru S Dutt ... Mercedes Gonzalez Juarrero
    A modified BPaL regimen for tuberculosis treatment replaces linezolid with inhaled spectinamides without showing linezolid associated adverse effects.
    1. Evolutionary Biology

    Alasemenia, the earliest ovule with three wings and without cupule

    Deming Wang, Jiangnan Yang ... Pu Huang
    Early seeds without cupules evolved functions in wind dispersal and probable photosynthetic nutrition and three-winged seeds are more adapted to wind dispersal than seeds with one, two, or four wings.
    1. Immunology and Inflammation

    LPS-induced systemic inflammation is suppressed by the PDZ motif peptide of ZO-1 via regulation of macrophage M1/M2 polarization

    Hyun-Chae Lee, Sun-Hee Park ... Kyoung Seob Song
    PEGylated PDZ peptide reduces LPS-induced systemic inflammation, restores tissue integrity, decreases pro-inflammatory cytokines, and modulates macrophage populations, showing potential as a therapeutic for systemic inflammation.
    1. Cancer Biology
    2. Immunology and Inflammation

    A novel bioinformatics pipeline for the identification of immune inhibitory receptors as potential therapeutic targets

    Akashdip Singh, Alberto Miranda Bedate ... Linde Meyaard
    A bioinformatics pipeline describes 390 putative, novel inhibitory receptors, to facilitate targeted therapeutic strategies for diverse immune cell types in cancer therapy.
    1. Biochemistry and Chemical Biology

    DTX3L ubiquitin ligase ubiquitinates single-stranded nucleic acids

    Emily L Dearlove, Chatrin Chatrin ... Danny T Huang
    Biochemical and structural analyses reveal direct ubiquitin modification of single-stranded nucleic acids, catalysed by the DTX3L ubiquitin ligase.
    1. Evolutionary Biology

    Ventral Morphology and Ecological Implications of Cindarella eucalla (Artiopoda, Xandarellida) from Chengjiang Biota, China

    Maoyin Zhang, Yu Liu ... Xianguang Hou
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Microbiology and Infectious Disease
    2. Neuroscience

    Olfactory basis for essential amino acid perception during foraging in Caenorhabditis elegans

    Ritika Siddiqui, Nikita Mehta ... Varsha Singh
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
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