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BMP2 and 7 synergize with H3.3K27M epigenetic context to establish a quiescent but invasive state in pediatric diffuse midline gliomas.

Sequence analyses show a pfhrp3 deletion mechanism involves duplication of chromosome 11 segment, which is normally removed via negative selection, and specific conditions are needed for spread including low transmission.

CUT-Tag is used to identify super-enhancers (SEs) for the first time in gastric cancer, and the mRNA decay mechanism activated by SE-driven ZFP36L1 in infiltrative gastric cancer along with innovative experimental evidence demonstrating SPI1/ZFP36L1/HDAC3/PD-L1 signaling axis are presented.

Genetic manipulations reveal how the spatiotemporal expression pattern of two RNA-binding proteins regulates the eventual number of motoneurons in a Drosophila neuronal lineage.

A modelling-based analysis reveals a novel type of selectivity for chromatic contrast in a mouse retinal ganglion cell type, and experimental evidence shows that this feature makes this cell type well suited for detecting behaviourally relevant changes in visual context.

c-di-GMP and HipH function as a toxin-antitoxin-like module to regulate persister cell formation in bacterial biofilms.

The retrieval of whole genomes from museum specimens from the extinct Xerxes Blue butterfly shows signals of population decline that could be use to identify present-day endangered insect species.

Deficiency or pharmacological inhibition of O-glcNac transferase (OGT) enhances tumor immunity in colorectal cancer models.