Posttranslational modifications of tubulins regulate axonal growth and regeneration by controlling the stabilities of microtubules or modulating their interactions with microtubule-associated proteins.
A biochemical approach shows co-phase separation of CCL5 with heparan sulfate establishes a specific chemokine concentration gradient for chemotactic activity.
Thomas Morgan Li, Victoria Zyulina ... Theresa T Lu
Interferon contributes to photosensitivity at least in part by causing Langerhans cell ADAM17 dysfunction, raising the possibility that anifrolumab ameliorates lupus skin disease in part by restoring Langerhans cell function.
A gene expression data-informed model reveals that a small fraction of interferon-producing cells can effectively constrain early virus spread in epithelial tissue, elucidating connections between critical dynamics and infection heterogeneity.
Dopaminergic and serotonergic neurons in the dorsal raphe nucleus have distinct electrical and morphological properties, which are differentially altered following dopamine and noradrenaline depletion.
